Literature DB >> 11206444

New anti-MRSA cephalosporins with a basic aminopyridine at the C-7 position.

A Cho1, T W Glinka, M Ludwikow, A T Fan, M Wang, S J Hecker.   

Abstract

Incorporation of a basic aminopyridine into the C-7 position of 3-(amine-substituted arylthio)-3-norcephalosporins, as in 3, afforded high potency against MRSA and acceptable solubility for intravenous administration.

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Year:  2001        PMID: 11206444     DOI: 10.1016/s0960-894x(00)00603-x

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN: 0960-894X            Impact factor:   2.823


  1 in total

1.  In vitro activity of S-3578, a new broad-spectrum cephalosporin active against methicillin-resistant staphylococci.

Authors:  Takaji Fujimura; Yoshinori Yamano; Isamu Yoshida; Jingoro Shimada; Shogo Kuwahara
Journal:  Antimicrob Agents Chemother       Date:  2003-03       Impact factor: 5.191

  1 in total

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