| Literature DB >> 1120471 |
Abstract
Conversion of estradiol and estrone to catechol estrogens by rat hypothalamic tissue but not by the cerebral cortex was demonstrated from the incubation of these tissues with estradiol-2-3H and estrone-2-3H and monitoring the incorporation of tritium into water. Direct evidence for this transformation was obtained by isolating the labelled phenazine derivative of 2-hydroxyestrone after hypothalamic incubation with estrone-4-14C.Entities:
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Year: 1975 PMID： 1120471 DOI： 10.1210/endo-96-4-1054
Source DB: PubMed Journal: Endocrinology ISSN： 0013-7227 Impact factor: 4.736