Literature DB >> 11204115

Depth dose-equivalent and effective energies of photoneutrons generated by 6-18 MV X-ray beams for radiotherapy.

F d'Errico1, M Luszik-Bhadra, R Nath, B R Siebert, U Wolf.   

Abstract

Photoneutron production was investigated on Siemens KD 2 and Varian Clinac accelerators operating in the 6-18 MV range. Neutron dose equivalent rates were measured on the surface of a water phantom at the isocenter of the accelerators and also inside the phantom at depths of 1, 5, and 10 cm and off-axis distances of 0, 20, and 50 cm. Superheated drop detectors based on dichlorofluoromethane and etched-track detectors with boronated converters were employed in this study. The energy response of these detectors permits a direct measurement of dose equivalent without prior knowledge of the neutron energy spectra. Dose equivalent rates were assessed using the Q(L) relationship from ICRP publication 60, as well as using earlier data from ICRP publication 21. This permitted both a comparison with previously published data and an assessment of the impact of the recent ICRP recommendations--which were found to increase the dose equivalent levels by about 30%. In addition, the depth corresponding to 50% of maximum dose equivalent, dH50, was determined along the central axis of the beams and at 50 cm off-axis. Monte Carlo neutron transport calculations were performed to determine the depth-dose equivalent distributions in a phantom irradiated with monoenergetic neutrons. Effective energies of the photoneutron spectra were then estimated by comparing our measured dH50 values to those calculated for monoenergetic neutrons. It was found that the effective photoneutron energy is 1.8-2.1 MeV within the 10-18 MV x-ray beams, and it is 0.5-0.8 MeV for photoneutrons transmitted through the accelerator head. Data from this work cover most of the x-ray beam energies in clinical use and permit an assessment of integral dose values as well as specific organ doses to a radiotherapy patient.

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Year:  2001        PMID: 11204115     DOI: 10.1097/00004032-200101000-00003

Source DB:  PubMed          Journal:  Health Phys        ISSN: 0017-9078            Impact factor:   1.316


  8 in total

1.  Neutron spectra and dose equivalents calculated in tissue for high-energy radiation therapy.

Authors:  Stephen F Kry; Rebecca M Howell; Mohammad Salehpour; David S Followill
Journal:  Med Phys       Date:  2009-04       Impact factor: 4.071

Review 2.  A review on photoneutrons characteristics in radiation therapy with high-energy photon beams.

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Journal:  Rep Pract Oncol Radiother       Date:  2010-09-22

3.  Monte Carlo characterizations mapping of the (γ,n) and (n,γ) photonuclear reactions in the high energy X-ray radiation therapy.

Authors:  Hosein Ghiasi
Journal:  Rep Pract Oncol Radiother       Date:  2013-07-31

4.  Quasi-IMAT technique and secondary cancer risk in prostate cancer.

Authors:  Judith Alvarez Moret; Oliver Koelbl; Ludwig Bogner
Journal:  Strahlenther Onkol       Date:  2009-04-16       Impact factor: 3.621

Review 5.  A review of dosimetry studies on external-beam radiation treatment with respect to second cancer induction.

Authors:  X George Xu; Bryan Bednarz; Harald Paganetti
Journal:  Phys Med Biol       Date:  2008-06-09       Impact factor: 3.609

6.  Breakthrough whole body energy-specific and tissue-specific photoneutron dosimetry by novel miniature neutron dosimeter/spectrometer.

Authors:  Mehdi Sohrabi; Morteza Ebrahimzadeh Torkamani
Journal:  Sci Rep       Date:  2021-10-15       Impact factor: 4.379

7.  Semi-experimental assessment of neutron equivalent dose and secondary cancer risk for off-field organs in glioma patients undergoing 18-MV radiotherapy.

Authors:  Soheil Elmtalab; Iraj Abedi; Zahra Alirezaei; Mohammad Hossein Choopan Dastjerdi; Ghazale Geraily; Amir Hossein Karimi
Journal:  PLoS One       Date:  2022-07-29       Impact factor: 3.752

8.  Hodgkin's lymphoma emerging radiation treatment techniques: trade-offs between late radio-induced toxicities and secondary malignant neoplasms.

Authors:  Laura Cella; Manuel Conson; Maria Cristina Pressello; Silvia Molinelli; Uwe Schneider; Vittorio Donato; Roberto Orecchia; Marco Salvatore; Roberto Pacelli
Journal:  Radiat Oncol       Date:  2013-01-30       Impact factor: 3.481

  8 in total

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