| Literature DB >> 11201878 |
W J Britton1, E Martin, A T Kamath, K D Neupane, P W Roche.
Abstract
We have investigated the effect of subunit vaccines against infection with Mycobacterium leprae, employing DNA plasmids as the vaccine vectors, and the immunodominant 35 kDa protein of M. leprae as the candidate antigen. A DNA vaccine that expresses the M. leprae 35 kDa protein both stimulated interferon-gamma (IFN gamma)-secreting T cells in mice, and demonstrated protection against M. leprae-infection of mice.Entities:
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Year: 2000 PMID： 11201878
Source DB: PubMed Journal: Lepr Rev ISSN： 0305-7518 Impact factor: 0.537