Literature DB >> 11198819

Purification and characterization of a lectin from the mushroom Mycoleptodonoides aitchisonii.

H Kawagishi1, J Takagi, T Taira, T Murata, T Usui.   

Abstract

A lectin was isolated from the mushroom Mycoleptodonoides aitchisonii by means of affinity chromatography on bovine submaxillary mucin (BSM)-Toyopearl and gel filtration on Superose 12 HR10/30 using a FPLC system. This lectin is composed of four identical 16 kDa subunits and the molecular mass of the intact lectin was estimated to be 64 kDa by gel filtration. In a hemagglutination inhibition assay, it exhibited strong sugar-binding specificity towards asialo-BSM among the mono- or oligo-saccharides and glycoproteins tested. The binding specificity of the lectin was also examined by surface plasmon resonance analysis.

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Year:  2001        PMID： 11198819     DOI： 10.1016/s0031-9422(00)00351-4

Source DB:  PubMed          Journal:  Phytochemistry        ISSN： 0031-9422            Impact factor:   4.072


  3 in total

1.  A novel lectin with antiproliferative and HIV-1 reverse transcriptase inhibitory activities from dried fruiting bodies of the monkey head mushroom Hericium erinaceum.

Authors:  Yanrui Li; Guoqing Zhang; Tzi Bun Ng; Hexiang Wang
Journal:  J Biomed Biotechnol       Date:  2010-06-13

Review 2.  Mushroom lectins: specificity, structure and bioactivity relevant to human disease.

Authors:  Mohamed Ali Abol Hassan; Razina Rouf; Evelin Tiralongo; Tom W May; Joe Tiralongo
Journal:  Int J Mol Sci       Date:  2015-04-08       Impact factor: 5.923

3.  Immunomodulatory Activities of a Fungal Protein Extracted from Hericium erinaceus through Regulating the Gut Microbiota.

Authors:  Chen Diling; Zheng Chaoqun; Yang Jian; Li Jian; Su Jiyan; Xie Yizhen; Lai Guoxiao
Journal:  Front Immunol       Date:  2017-06-12       Impact factor: 7.561
  3 in total

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