Literature DB >> 11198816

Cytotoxic labdane diterpenoids from Croton oblongifolius.

S Roengsumran1, A Petsom, N Kuptiyanuwat, T Vilaivan, N Ngamrojnavanich, C Chaichantipyuth, S Phuthong.   

Abstract

Three labdane diterpenoids, 2-acetoxy-3-hydroxy-labda-8(17),12(E)-14-triene, 3-acetoxy-2-hydroxy-labda-8(17),12(E)-14-triene, and 2,3-dihydroxy-labda-8(17),12(E),14-triene were isolated from stem bark of Croton oblongifolius. Their structures were established by spectroscopic data, and each was also tested for cytotoxicity against various human tumor cell lines. The latter compound showed non-specific, moderate, cytotoxicities against all the cell lines; whereas the first two compounds were less active.

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Year:  2001        PMID: 11198816     DOI: 10.1016/s0031-9422(00)00358-7

Source DB:  PubMed          Journal:  Phytochemistry        ISSN: 0031-9422            Impact factor:   4.072


  4 in total

1.  Direct effect of croton oil on intestinal epithelial cells and colonic smooth muscle cells.

Authors:  Xin Wang; Mei Lan; Han-Ping Wu; Yong-Quan Shi; Ju Lu; Jie Ding; Kai-Cun Wu; Jian-Ping Jin; Dai-Ming Fan
Journal:  World J Gastroenterol       Date:  2002-02       Impact factor: 5.742

2.  Evaluation of the anticancer potential of six herbs against a hepatoma cell line.

Authors:  Natthida Weerapreeyakul; Apiyada Nonpunya; Sahapat Barusrux; Thaweesak Thitimetharoch; Bungorn Sripanidkulchai
Journal:  Chin Med       Date:  2012-06-10       Impact factor: 5.455

3.  Isolation, Characterization and Antiproliferative Activity of New Metabolites from the South African Endemic Red Algal Species Laurencia alfredensis.

Authors:  Godwin A Dziwornu; Mino R Caira; Jo-Anne de la Mare; Adrienne L Edkins; John J Bolton; Denzil R Beukes; Suthananda N Sunassee
Journal:  Molecules       Date:  2017-03-23       Impact factor: 4.411

4.  Potential of Thai Herbal Extracts on Lung Cancer Treatment by Inducing Apoptosis and Synergizing Chemotherapy.

Authors:  Juthathip Poofery; Patompong Khaw-On; Subhawat Subhawa; Bungorn Sripanidkulchai; Apichat Tantraworasin; Somcharoen Saeteng; Sopon Siwachat; Nirush Lertprasertsuke; Ratana Banjerdpongchai
Journal:  Molecules       Date:  2020-01-06       Impact factor: 4.411

  4 in total

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