| Literature DB >> 11197330 |
E A Hallinan1, T J Hagen, S Tsymbalov, A Stapelfeld, M A Savage.
Abstract
8-Chlorodibenz[b,f][1,4]oxazepine-10(11H)-carboxylic acid, 2-[1-oxo-3-(4-pyridinyl)propyl]hydrazide, monohydrochloride (1, SC-51089) is a functional PGE2 antagonist selective for the EP1 receptor subtype with antinociceptive activity. Analogues of SC-51089, in which the diacylhydrazine moiety has been replaced with 2,4-disubstituted-oxazoles and-thiazoles, are described.Entities:
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Year: 2001 PMID： 11197330 DOI： 10.1016/s0968-0896(00)00229-7
Source DB: PubMed Journal: Bioorg Med Chem ISSN： 0968-0896 Impact factor: 3.641