Literature DB >> 11197320

Phylogenetic origin of a secondary pathway: the case of pyrrolizidine alkaloids.

D Ober1, T Hartmann.   

Abstract

Recent studies have revealed high sequence similarity between homospermidine synthase (HSS), the first pathway-specific enzyme in the biosynthesis of pyrrolizidine alkaloids, a class of sporadically occurring plant defence compounds, and deoxyhypusine synthase (DHS), a ubiquitous enzyme involved in the post-translational activation of the eukaryotic initiation factor 5A (eIF5A). The recruitment of DHS during the evolution of the alkaloid pathway is discussed and interpreted as evolution by change of function.

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Year:  2000        PMID： 11197320     DOI： 10.1023/a:1026597621646

Source DB:  PubMed          Journal:  Plant Mol Biol        ISSN： 0167-4412            Impact factor:   4.076


  11 in total

Review 1.  Aflatoxigenicity in Aspergillus: molecular genetics, phylogenetic relationships and evolutionary implications.

Authors:  Jeffrey W Cary; Kenneth C Ehrlich
Journal:  Mycopathologia       Date:  2006-09       Impact factor: 2.574

2.  From amino acid to glucosinolate biosynthesis: protein sequence changes in the evolution of methylthioalkylmalate synthase in Arabidopsis.

Authors:  Jan-Willem de Kraker; Jonathan Gershenzon
Journal:  Plant Cell       Date:  2011-01-04       Impact factor: 11.277

3.  Rosmarinic acid synthase is a new member of the superfamily of BAHD acyltransferases.

Authors:  Anja Berger; Juliane Meinhard; Maike Petersen
Journal:  Planta       Date:  2006-09-19       Impact factor: 4.116

4.  Polyphyletic origin of pyrrolizidine alkaloids within the Asteraceae. Evidence from differential tissue expression of homospermidine synthase.

Authors:  Sven Anke; Daniel Niemüller; Stefanie Moll; Robert Hänsch; Dietrich Ober
Journal:  Plant Physiol       Date:  2004-11-19       Impact factor: 8.340

5.  New aspect of plant-rhizobia interaction: alkaloid biosynthesis in Crotalaria depends on nodulation.

Authors:  Simon Irmer; Nora Podzun; Dorothee Langel; Franziska Heidemann; Elisabeth Kaltenegger; Brigitte Schemmerling; Christoph-Martin Geilfus; Christian Zörb; Dietrich Ober
Journal:  Proc Natl Acad Sci U S A       Date:  2015-03-16       Impact factor: 11.205

6.  Insights into polyamine metabolism: homospermidine is double-oxidized in two discrete steps by a single copper-containing amine oxidase in pyrrolizidine alkaloid biosynthesis.

Authors:  Mahmoud M Zakaria; Thomas Stegemann; Christian Sievert; Lars H Kruse; Elisabeth Kaltenegger; Ulrich Girreser; Serhat S Çiçek; Manfred Nimtz; Dietrich Ober
Journal:  Plant Cell       Date:  2022-05-24       Impact factor: 12.085

7.  Cell-specific expression of homospermidine synthase, the entry enzyme of the pyrrolizidine alkaloid pathway in Senecio vernalis, in comparison with its ancestor, deoxyhypusine synthase.

Authors:  Stefanie Moll; Sven Anke; Uwe Kahmann; Robert Hänsch; Thomas Hartmann; Dietrich Ober
Journal:  Plant Physiol       Date:  2002-09       Impact factor: 8.340

8.  Evolutionary routes to biochemical innovation revealed by integrative analysis of a plant-defense related specialized metabolic pathway.

Authors:  Gaurav D Moghe; Bryan J Leong; Steven M Hurney; A Daniel Jones; Robert L Last
Journal:  Elife       Date:  2017-08-30       Impact factor: 8.140

9.  Repeated evolution of the pyrrolizidine alkaloid-mediated defense system in separate angiosperm lineages.

Authors:  Andreas Reimann; Niknik Nurhayati; Anita Backenköhler; Dietrich Ober
Journal:  Plant Cell       Date:  2004-10       Impact factor: 11.277

10.  Metabolic Profiling of Pyrrolizidine Alkaloids in Foliage of Two Echium spp. Invaders in Australia--A Case of Novel Weapons?

Authors:  Dominik Skoneczny; Paul A Weston; Xiaocheng Zhu; Geoff M Gurr; Ragan M Callaway; Leslie A Weston
Journal:  Int J Mol Sci       Date:  2015-11-06       Impact factor: 5.923
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