Literature DB >> 11197284

Effect of age on differences in upper esophageal sphincter and pharynx pressures between patients with dysphagia and control subjects.

H K Meier-Ewert1, M A Van Herwaarden, R M Gideon, J A Castell, S Achem, D O Castell.   

Abstract

OBJECTIVES: The aim of this study was to explore the effect of age and food consistency on manometric data of the swallow sequence in patients with dysphagia.
METHODS: Manometric data from 41 patients (age range, 32-88 yr) and 41 age-matched control subjects was examined for differences between subgroups < 60 yr and > or = 60 yr of age, as well as for changes with food consistency.
RESULTS: Only pharynx peak pressure showed an age-dependent decrease (144.1 +/- 21.4 mm Hg vs 95.8 +/- 15.1 mm Hg, p < 0.05) in patients. Significant higher upper esophageal sphincter residual pressure and delayed onset of upper esophageal sphincter relaxation were noted in patients aged <60 yr compared to age-matched controls, whereas only pharynx peak pressure was significantly lower in patients compared to controls aged > or = 60 yr. Food consistency did not have a consistent effect on manometric results in patients with dysphagia.
CONCLUSIONS: This is the first study to systematically explore the influence of age and food consistency on manometric parameters in dysphagia patients. These results may provide useful insights when identifying actual manometric abnormalities in patients with dysphagia. They also suggest possible different underlying mechanisms of dysphagia in younger versus older patients.

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Year:  2001        PMID: 11197284     DOI: 10.1111/j.1572-0241.2001.03448.x

Source DB:  PubMed          Journal:  Am J Gastroenterol        ISSN: 0002-9270            Impact factor:   10.864


  6 in total

1.  Pharyngeal contractile and regulatory characteristics are distinct during nutritive oral stimulus in preterm-born infants: Implications for clinical and research applications.

Authors:  Varsha Prabhakar; Kathryn A Hasenstab; Erika Osborn; Lai Wei; Sudarshan R Jadcherla
Journal:  Neurogastroenterol Motil       Date:  2019-05-26       Impact factor: 3.598

2.  The McGill ingestive skills assessment predicts time to death in an elderly population with neurogenic dysphagia: preliminary evidence.

Authors:  Heather C Lambert; Michal Abrahamowicz; Michael Groher; Sharon Wood-Dauphinee; Erika G Gisel
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3.  Significance of nonrespiratory airflow during swallowing.

Authors:  Martin B Brodsky; David H McFarland; Yvonne Michel; Suzanne B Orr; Bonnie Martin-Harris
Journal:  Dysphagia       Date:  2011-07-07       Impact factor: 3.438

4.  Upper esophageal sphincter abnormalities are strongly predictive of treatment response in patients with achalasia.

Authors:  Simon C Mathews; Maria Ciarleglio; Yamile Haito Chavez; John O Clarke; Ellen Stein; Bani Chander Roland
Journal:  World J Clin Cases       Date:  2014-09-16       Impact factor: 1.337

Review 5.  [Endoscopic therapy methods for gastroesophageal reflux].

Authors:  B Schumacher; H Neuhaus
Journal:  Chirurg       Date:  2005-04       Impact factor: 0.955

6.  Pathophysiology and treatment of patients with globus sensation--from the viewpoint of esophageal motility dysfunction.

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  6 in total

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