Literature DB >> 111964

Anticonvulsant action of YG 19-256 in baboons with photosensitive epilepsy.

B S Meldrum, R W Horton.   

Abstract

YG 19-256, 4-(1,3,4,9b-tetrahydro-5 methyl-2H-indeno[1,2-c]pyridine-2-yl)-2-butanone methane sulphonate, 1-3 mg/kg i.v., abolished or reduced photically-induced myoclonic responses for 1.5-6.5 h in baboons, Papio papio, without producing signs of acute neurological toxicity.

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Year:  1979        PMID: 111964     DOI: 10.1007/bf01968255

Source DB:  PubMed          Journal:  Experientia        ISSN: 0014-4754


  3 in total

1.  Inter-group aggression in mice: a new method for testing the effects of centrally active drugs.

Authors:  P P Zwirner; R D Porsolt; D M Loew
Journal:  Psychopharmacologia       Date:  1975-12-31

2.  A primate model for testing anticonvulsant drugs.

Authors:  B S Meldrum; R W Horton; P A Toseland
Journal:  Arch Neurol       Date:  1975-05

3.  An animal model of light sensitive epilepsy.

Authors:  K F Killam; E K Killam; R Naquet
Journal:  Electroencephalogr Clin Neurophysiol       Date:  1967-06
  3 in total

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