Literature DB >> 11194967

[Fractionated radiotherapy of intracranial meningiomas and neurinomas].

J P Maire1, V Vendrely, M Dautheribes, N Bonichon, V Darrouzet.   

Abstract

In most institutions, surgical excision remains the standard treatment of meningiomas and neurinomas; the aim of surgery is complete resection. However, total removal is not always feasible without significant morbidity and in some cases, the patient's condition contraindicates surgery. For incompletely excised tumors, recurrences will have consequences on neurological functions. There are now many reports in the literature confirming the fact that radiotherapy significantly decreases the incidence of recurrence of incompletely resected benign tumors and that it can replace surgery in some situations where an operation would involve considerable danger or permanent neurological damage: about 80 to 90% of such tumors are controlled with fractionated radiotherapy. Stereotaxic and three-dimensional treatment planning techniques increase local control and central nervous system tolerance so that the respective place of surgery and radiotherapy needs to be redefined, considering efficacy and morbidity of these two therapeutic means. In this article, we limit our remarks to fractionated radiotherapy and, after a review of the literature, we discuss the indications, volume evaluations and the techniques currently used.

Entities:  

Mesh:

Year:  2000        PMID: 11194967

Source DB:  PubMed          Journal:  Cancer Radiother        ISSN: 1278-3218            Impact factor:   1.018


  1 in total

1.  Linac-based stereotactic radiotherapy and radiosurgery in patients with meningioma.

Authors:  David Kaul; Volker Budach; Reinhard Wurm; Arne Gruen; Lukas Graaf; Piet Habbel; Harun Badakhshi
Journal:  Radiat Oncol       Date:  2014-03-20       Impact factor: 3.481

  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.