Literature DB >> 11193814

A novel VIP responsive gene. Activity dependent neuroprotective protein.

I Gozes1, R Zamostiano, A Pinhasov, M Bassan, E Giladi, R A Steingart, D E Brenneman.   

Abstract

Activity dependent neuroprotective protein (ADNP, 828 amino acids, pI 5.99) is a glial-derived protein that contains a femtomolar active neuroprotective peptide, NAPVSIPQ (NAP). VIP induces a two- to threefold increase in ADNP mRNA in astrocytes, suggesting that ADNP is a VIP-responsive gene. ADNP is widely distributed in the mouse hippocampus, cerebellum, and cerebral cortex. VIP has been shown to possess neuroprotective activity that may be exerted through the activation of glial proteins. We suggest that ADNP may be part of the VIP protection pathway through the femtomolar-acting NAP and through putative interaction with other macromolecules.

Entities:  

Mesh：

Substances：

Year:  2000        PMID： 11193814     DOI： 10.1111/j.1749-6632.2000.tb06957.x

Source DB:  PubMed          Journal:  Ann N Y Acad Sci        ISSN： 0077-8923            Impact factor:   5.691


  10 in total

1.  NAP accelerates the performance of normal rats in the water maze.

Authors:  Illana Gozes; Roy Alcalay; Eliezer Giladi; Albert Pinhasov; Sharon Furman; Douglas E Brenneman
Journal:  J Mol Neurosci       Date:  2002 Aug-Oct       Impact factor: 3.444

Review 2.  VPAC receptors: structure, molecular pharmacology and interaction with accessory proteins.

Authors:  Alain Couvineau; Marc Laburthe
Journal:  Br J Pharmacol       Date:  2012-05       Impact factor: 8.739

3.  Subcellular localization and secretion of activity-dependent neuroprotective protein in astrocytes.

Authors:  Sharon Furman; Ruth A Steingart; Shmuel Mandel; Janet M Hauser; Douglas E Brenneman; Illana Gozes
Journal:  Neuron Glia Biol       Date:  2004-08

4.  Nitric oxide-NGF mediated PPTA/SP, ADNP, and VIP expression in the peripheral nervous system.

Authors:  Thimmasettappa Thippeswamy; Mark R Howard; Anna Siobhan Cosgrave; Daleep Kumar Arora; Jennifer S McKay; John P Quinn
Journal:  J Mol Neurosci       Date:  2007-09-11       Impact factor: 3.444

5.  D-SAL and NAP: Two Peptides Sharing a SIP Domain.

Authors:  Illana Gozes; Shlomo Sragovich; Yulie Schirer; Anat Idan-Feldman
Journal:  J Mol Neurosci       Date:  2016-06       Impact factor: 3.444

Review 6.  Strategies for intranasal delivery of therapeutics for the prevention and treatment of neuroAIDS.

Authors:  Leah R Hanson; William H Frey
Journal:  J Neuroimmune Pharmacol       Date:  2006-09-15       Impact factor: 4.147

7.  Vasoactive intestinal polypeptide immunoreactivity in the human cerebellum: qualitative and quantitative analyses.

Authors:  Vincenzo Benagiano; Paolo Flace; Loredana Lorusso; Anna Rizzi; Lorenzo Bosco; Raffaele Cagiano; Glauco Ambrosi
Journal:  J Anat       Date:  2009-06-22       Impact factor: 2.610

8.  The Role of Clinical Proteomics, Lipidomics, and Genomics in the Diagnosis of Alzheimer's Disease.

Authors:  Ian James Martins
Journal:  Proteomes       Date:  2016-03-31

9.  The transcriptional regulator ADNP links the BAF (SWI/SNF) complexes with autism.

Authors:  Geert Vandeweyer; Céline Helsmoortel; Anke Van Dijck; Anneke T Vulto-van Silfhout; Bradley P Coe; Raphael Bernier; Jennifer Gerdts; Liesbeth Rooms; Jenneke van den Ende; Madhura Bakshi; Meredith Wilson; Ann Nordgren; Laura G Hendon; Omar A Abdulrahman; Corrado Romano; Bert B A de Vries; Tjitske Kleefstra; Evan E Eichler; Nathalie Van der Aa; R Frank Kooy
Journal:  Am J Med Genet C Semin Med Genet       Date:  2014-08-28       Impact factor: 3.908

10.  Expression of activity-dependent neuroprotective protein in the immune system: possible functions and relevance to multiple sclerosis.

Authors:  Manjit Braitch; Kiyokazu Kawabe; Mukanthu Nyirenda; Lucie Jean Gilles; R Adrian Robins; Bruno Gran; Sean Murphy; Louise Showe; Cris S Constantinescu
Journal:  Neuroimmunomodulation       Date:  2009-11-17       Impact factor: 2.492
  10 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.