Literature DB >> 11190398

Anthracene derivatives from Auxemma oncocalyx.

W B Marques1, H S dos Santos, O D Pessoa, R Braz-Filho, T L Lemos.   

Abstract

Three anthracene derivatives, auxenone, oncocalyxonol and auxemim, were isolated from Auxemma ontocalyx. The structures of these compounds as 1,4,8-trihydroxy-2-methoxy-5-methyl-9,10-anthraquinone, rel-9alpha,11alpha-epoxy-1,4,8alpha,11alpha-tetrahydroxy-2-methoxy-8a beta-methyl-5,6,7,8,8a,9, 10,10a beta-octahydro-10-anthracenone and rel-8alpha,11beta-epoxy-2,11-dimethoxy-8a beta-methyl-5,6,7,8,8a,9-hexahydro-1,4-anthracenedione were determined by analysis of spectral data (1D and 2D NMR, IR, HREIMS and UV).

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Year:  2000        PMID: 11190398     DOI: 10.1016/s0031-9422(00)00325-3

Source DB:  PubMed          Journal:  Phytochemistry        ISSN: 0031-9422            Impact factor:   4.072


  4 in total

1.  Oncocalyxone A inhibits human platelet aggregation by increasing cGMP and by binding to GP Ibalpha glycoprotein.

Authors:  M A D Ferreira; N R F do Nascimento; C M de Sousa; O D L Pessoa; T L G de Lemos; J S Ventura; M Schattner; A M Chudzinski-Tavassi
Journal:  Br J Pharmacol       Date:  2008-06-02       Impact factor: 8.739

2.  Functionalization of anthracene: A selective route to brominated 1,4-anthraquinones.

Authors:  Kiymet Berkil Akar; Osman Cakmak; Orhan Büyükgüngör; Ertan Sahin
Journal:  Beilstein J Org Chem       Date:  2011-07-29       Impact factor: 2.883

3.  Magnetic nanosystem for cancer therapy using oncocalyxone a, an antitomour secondary metabolite isolated from a Brazilian plant.

Authors:  Antônio C H Barreto; Vivian R Santiago; Rafael M Freire; Selma E Mazzetto; Juliano C Denardin; Giuseppe Mele; Igor M Cavalcante; Maria E N P Ribeiro; Nágila M P S Ricardo; Tamara Gonçalves; Luigi Carbone; Telma L G Lemos; Otília D L Pessoa; Pierre B A Fechine
Journal:  Int J Mol Sci       Date:  2013-09-05       Impact factor: 5.923

4.  Highly brominated anthracenes as precursors for the convenient synthesis of 2,9,10-trisubstituted anthracene derivatives.

Authors:  Osman Cakmak; Leyla Aydogan; Kiymet Berkil; Ilhami Gulcin; Orhan Buyukgungor
Journal:  Beilstein J Org Chem       Date:  2008-12-10       Impact factor: 2.883

  4 in total

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