| Literature DB >> 11188727 |
Abstract
A cell ensures that its genome is replicated only once during its division cycle through a process called licensing. In an enlightening Perspective, Lygerou and Nurse explain how binding of the Geminin protein to Cdt1 blocks the binding of licensing factors to chromatin, inhibiting the onset of S phase (Wohlschlegel et al.).Entities:
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Year: 2000 PMID： 11188727
Source DB: PubMed Journal: Science ISSN： 0036-8075 Impact factor: 47.728