Literature DB >> 11187046

Cell biology. Actin' up with Rac1.

N J Colley1.   

Abstract

The elegant architecture of photoreceptor cells in the retina is dependent on organization of the actin cytoskeleton during eye development. But what drives this organization? In an equally elegant Perspective, Colley explains new findings in fruit flies (Chang and Ready) that point to the photopigment rhodopsin and its signaling molecule the Rho GTPase Drac1 as the orchestrators of actin organization and the consequent assembly of the sensory membrane in the photoreceptor cell.

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Year:  2000        PMID: 11187046     DOI: 10.1126/science.290.5498.1902

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  9 in total

Review 1.  Syntrophins entangled in cytoskeletal meshwork: Helping to hold it all together.

Authors:  Sahar S Bhat; Roshia Ali; Firdous A Khanday
Journal:  Cell Prolif       Date:  2018-12-04       Impact factor: 6.831

2.  Dynamin- and Rab5-dependent endocytosis is required to prevent Drosophila photoreceptor degeneration.

Authors:  Noelia Pinal; Franck Pichaud
Journal:  J Cell Sci       Date:  2011-04-12       Impact factor: 5.285

3.  Altered gene regulation and synaptic morphology in Drosophila learning and memory mutants.

Authors:  Zhuo Guan; Lauren K Buhl; William G Quinn; J Troy Littleton
Journal:  Learn Mem       Date:  2011-03-21       Impact factor: 2.460

4.  The Drosophila radish gene encodes a protein required for anesthesia-resistant memory.

Authors:  Elisabeth Folkers; Scott Waddell; William G Quinn
Journal:  Proc Natl Acad Sci U S A       Date:  2006-11-06       Impact factor: 11.205

5.  Small interfering RNA targeting Rac1 sensitizes colon cancer to dihydroartemisinin-induced cell cycle arrest and inhibited cell migration by suppressing NFκB activity.

Authors:  Peng Han; Ying Luan; Yanlong Liu; Zhiwei Yu; Jingwen Li; Zicheng Sun; Gang Chen; Binbin Cui
Journal:  Mol Cell Biochem       Date:  2013-04-05       Impact factor: 3.396

6.  PI3K and ERK-induced Rac1 activation mediates hypoxia-induced HIF-1α expression in MCF-7 breast cancer cells.

Authors:  Jun Du; Rui Xu; Zhenzhen Hu; Yinhui Tian; Yichao Zhu; Luo Gu; Lei Zhou
Journal:  PLoS One       Date:  2011-09-27       Impact factor: 3.240

7.  TIPE2 acts as a biomarker for GIST risk category and suppresses the viability and invasiveness of GIST cells.

Authors:  Zequn Li; Wei Zhang; Yi Li; Shougen Cao; Shanglong Liu; Liang Ning; Xuelong Jiao; Zimin Liu; Xiaoming Xing; Yujun Li; Yanbing Zhou
Journal:  Cell Biosci       Date:  2018-12-05       Impact factor: 7.133

8.  Role of SNTA1 in Rac1 activation, modulation of ROS generation, and migratory potential of human breast cancer cells.

Authors:  H F Bhat; R A Baba; M E Adams; F A Khanday
Journal:  Br J Cancer       Date:  2014-01-16       Impact factor: 7.640

9.  TIPE2 acts as a biomarker for tumor aggressiveness and suppresses cell invasiveness in papillary thyroid cancer (PTC).

Authors:  Wenyu Jia; Zequn Li; Junyu Chen; Lei Sun; Chuanqian Liu; Shaping Wang; Jingwei Chi; Jun Niu; Hong Lai
Journal:  Cell Biosci       Date:  2018-08-31       Impact factor: 7.133

  9 in total

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