Literature DB >> 11181132

Patients with active tuberculosis have increased expression of HIV coreceptors CXCR4 and CCR5 on CD4(+) T cells.

N P Juffermans1, P Speelman, A Verbon, J Veenstra, C Jie, S J van Deventer, T van Der Poll.   

Abstract

Expression of human immunodeficiency virus (HIV) coreceptors CXCR4 and CCR5 was found to be elevated on CD4(+) T cells (1) in blood samples obtained from patients with tuberculosis and (2) in blood samples obtained from healthy subjects and stimulated with mycobacterial lipoarabinomannan in vitro. These data suggest that the increase in HIV viremia that occurs in association with tuberculosis may result from up-regulation of CXCR4 and CCR5 on CD4(+) T cells, thereby causing acceleration of HIV infection.

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Year:  2001        PMID: 11181132     DOI: 10.1086/318701

Source DB:  PubMed          Journal:  Clin Infect Dis        ISSN: 1058-4838            Impact factor:   9.079


  12 in total

Review 1.  Immunology of Mycobacterium tuberculosis Infections.

Authors:  Jonathan Kevin Sia; Jyothi Rengarajan
Journal:  Microbiol Spectr       Date:  2019-07

2.  Chemokine receptor expression and modulation by Mycobacterium tuberculosis antigens on mononuclear cells from human lymphoid tissues.

Authors:  Mauricio A Arias; Adelis E Pantoja; Gabriela Jaramillo; Sara C Paris; Robin J Shattock; Luis F García; George E Griffin
Journal:  Immunology       Date:  2006-06       Impact factor: 7.397

Review 3.  Chemokines shape the immune responses to tuberculosis.

Authors:  Samantha R Slight; Shabaana A Khader
Journal:  Cytokine Growth Factor Rev       Date:  2012-11-16       Impact factor: 7.638

4.  Friends and foes of tuberculosis: modulation of protective immunity.

Authors:  S Brighenti; S A Joosten
Journal:  J Intern Med       Date:  2018-05-27       Impact factor: 8.989

5.  Distribution of the human immunodeficiency virus coreceptors CXCR4 and CCR5 on leukocytes of persons with human immunodeficiency virus type 1 infection and pulmonary tuberculosis: implications for pathogenesis.

Authors:  S Shalekoff; S Pendle; D Johnson; D J Martin; C T Tiemessen
Journal:  J Clin Immunol       Date:  2001-11       Impact factor: 8.317

6.  Lesion-Specific Immune Response in Granulomas of Patients with Pulmonary Tuberculosis: A Pilot Study.

Authors:  Selvakumar Subbian; Liana Tsenova; Mi-Jeong Kim; Helen C Wainwright; Annalie Visser; Nirmalya Bandyopadhyay; Joel S Bader; Petros C Karakousis; Gabriele B Murrmann; Linda-Gail Bekker; David G Russell; Gilla Kaplan
Journal:  PLoS One       Date:  2015-07-02       Impact factor: 3.240

7.  Predictors for Mortality among Multidrug-Resistant Tuberculosis Patients in Tanzania.

Authors:  Edson W Mollel; Jaffu O Chilongola
Journal:  J Trop Med       Date:  2017-07-20

8.  Demographic and clinical correlates of HIV-1 RNA levels in antiretroviral therapy-naive adults attending a tertiary hospital in Jos, Nigeria.

Authors:  Joseph Anejo-Okopi; Isaac Okoh Abah; Yakhat Barshep; Augustine Odo Ebonyi; Comfort Daniyam; Samson Ejiji Isa; Gomerep Simji; Stephen Oguche; Patricia Agaba; Patricia Lar; Oche Agbaji; John A Idoko
Journal:  J Virus Erad       Date:  2017-01-01

9.  Enhancement of HIV-1 infection and intestinal CD4+ T cell depletion ex vivo by gut microbes altered during chronic HIV-1 infection.

Authors:  Stephanie M Dillon; Eric J Lee; Andrew M Donovan; Kejun Guo; Michael S Harper; Daniel N Frank; Martin D McCarter; Mario L Santiago; Cara C Wilson
Journal:  Retrovirology       Date:  2016-01-14       Impact factor: 4.602

Review 10.  C-C chemokine receptor type five (CCR5): An emerging target for the control of HIV infection.

Authors:  Fatima Barmania; Michael S Pepper
Journal:  Appl Transl Genom       Date:  2013-05-26
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