| Literature DB >> 11179901 |
E Chevet1, P H Cameron, M F Pelletier, D Y Thomas, J J Bergeron.
Abstract
The endoplasmic reticulum is the entry point into the secretory pathway. To acquire a correct conformation, secretory proteins encounter the endoplasmic reticulum molecular machines of folding, quality control, signaling and disposal, which function as an integrated mechanism. The creation of such a molecular network, spatially regulated, suggests how the endoplasmic reticulum promotes the release of correctly folded secretory proteins.Mesh:
Substances:
Year: 2001 PMID: 11179901 DOI: 10.1016/s0959-440x(00)00168-8
Source DB: PubMed Journal: Curr Opin Struct Biol ISSN: 0959-440X Impact factor: 6.809