Literature DB >> 11179897

Characterisation of the transition states for protein folding: towards a new level of mechanistic detail in protein engineering analysis.

M Oliveberg1.   

Abstract

The field of protein folding now offers considerable excitement. Comparative studies of the transition-state structures for a series of protein families with analogous structures have helped to uncover the overall rules for protein folding. In addition, new protein engineering experiments that continuously follow the growth of the folding nucleus have started to fill in the missing details.

Mesh：

Year:  2001        PMID： 11179897     DOI： 10.1016/s0959-440x(00)00171-8

Source DB:  PubMed          Journal:  Curr Opin Struct Biol        ISSN： 0959-440X            Impact factor:   6.809


  32 in total

1.  Unspecific hydrophobic stabilization of folding transition states.

Authors:  Ana Rosa Viguera; Cristina Vega; Luis Serrano
Journal:  Proc Natl Acad Sci U S A       Date:  2002-04-16       Impact factor: 11.205

2.  Folding a protein in a computer: an atomic description of the folding/unfolding of protein A.

Authors:  Angel E García; José N Onuchic
Journal:  Proc Natl Acad Sci U S A       Date:  2003-11-17       Impact factor: 11.205

3.  Posttransition state desolvation of the hydrophobic core of the src-SH3 protein domain.

Authors:  Weihua Guo; Sotiria Lampoudi; Joan-Emma Shea
Journal:  Biophys J       Date:  2003-07       Impact factor: 4.033

4.  Experimental evaluation of topological parameters determining protein-folding rates.

Authors:  Erik J Miller; Kael F Fischer; Susan Marqusee
Journal:  Proc Natl Acad Sci U S A       Date:  2002-07-29       Impact factor: 11.205

5.  Scattered Hammond plots reveal second level of site-specific information in protein folding: phi' (beta++).

Authors:  Linda Hedberg; Mikael Oliveberg
Journal:  Proc Natl Acad Sci U S A       Date:  2004-05-10       Impact factor: 11.205

6.  Simulation, experiment, and evolution: understanding nucleation in protein S6 folding.

Authors:  Isaac A Hubner; Mikael Oliveberg; Eugene I Shakhnovich
Journal:  Proc Natl Acad Sci U S A       Date:  2004-05-18       Impact factor: 11.205

7.  What can one learn from experiments about the elusive transition state?

Authors:  Iksoo Chang; Marek Cieplak; Jayanth R Banavar; Amos Maritan
Journal:  Protein Sci       Date:  2004-08-04       Impact factor: 6.725

8.  Relationship of Leffler (Bronsted) alpha values and protein folding Phi values to position of transition-state structures on reaction coordinates.

Authors:  Alan R Fersht
Journal:  Proc Natl Acad Sci U S A       Date:  2004-09-21       Impact factor: 11.205

9.  Gating of acetylcholine receptor channels: brownian motion across a broad transition state.

Authors:  Anthony Auerbach
Journal:  Proc Natl Acad Sci U S A       Date:  2005-01-21       Impact factor: 11.205

10.  Spectrin R16: broad energy barrier or sequential transition states?

Authors:  Kathryn A Scott; Jane Clarke
Journal:  Protein Sci       Date:  2005-06       Impact factor: 6.725
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