Literature DB >> 11179891

DNA mismatch repair: MutS structures bound to mismatches.

T K Sixma1.   

Abstract

When DNA mismatch repair fails, the result is a mutator phenotype, which can lead to cancer in humans. Functional repair is dependent on the recognition of mismatches by a dimeric MutS protein, a homodimer in bacteria but a heterodimer in humans. Recent crystal structures of Thermus aquaticus and Escherichia coli MutS have revealed the structural heterodimeric nature of the bacterial proteins and provide new insights into their complicated ATP-dependent repair mechanism.

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Year:  2001        PMID： 11179891     DOI： 10.1016/s0959-440x(00)00169-x

Source DB:  PubMed          Journal:  Curr Opin Struct Biol        ISSN： 0959-440X            Impact factor:   6.809


  21 in total

1.  MutS recognition: multiple mismatches and sequence context effects.

Authors:  A Joshi; B J Rao
Journal:  J Biosci       Date:  2001-12       Impact factor: 1.826

2.  Nitrogen-regulated hypermutator strain of Synechococcus sp. for use in in vivo artificial evolution.

Authors:  Daniel Emlyn-Jones; G Dean Price; T John Andrews
Journal:  Appl Environ Microbiol       Date:  2003-11       Impact factor: 4.792

3.  DNA bending and unbending by MutS govern mismatch recognition and specificity.

Authors:  Hong Wang; Yong Yang; Mark J Schofield; Chunwei Du; Yonatan Fridman; Susan D Lee; Erik D Larson; James T Drummond; Eric Alani; Peggy Hsieh; Dorothy A Erie
Journal:  Proc Natl Acad Sci U S A       Date:  2003-11-21       Impact factor: 11.205

4.  A study on mutational dynamics of simple sequence repeats in relation to mismatch repair system in prokaryotic genomes.

Authors:  Pankaj Kumar; H A Nagarajaram
Journal:  J Mol Evol       Date:  2012-03-14       Impact factor: 2.395

5.  Mismatch-induced DNA unbending upon duplex opening.

Authors:  Chongli Yuan; Elizabeth Rhoades; Daniel M Heuer; Lynden A Archer
Journal:  Biophys J       Date:  2005-08-05       Impact factor: 4.033

6.  Coupling distant sites in DNA during DNA mismatch repair.

Authors:  Richard D Kolodner; Marc L Mendillo; Christopher D Putnam
Journal:  Proc Natl Acad Sci U S A       Date:  2007-07-30       Impact factor: 11.205

7.  Crystal structure of Bacillus stearothermophilus UvrA provides insight into ATP-modulated dimerization, UvrB interaction, and DNA binding.

Authors:  Danaya Pakotiprapha; Yoshihiko Inuzuka; Brian R Bowman; Geri F Moolenaar; Nora Goosen; David Jeruzalmi; Gregory L Verdine
Journal:  Mol Cell       Date:  2007-12-27       Impact factor: 17.970

8.  Mechanism of MutS searching for DNA mismatches and signaling repair.

Authors:  Ingrid Tessmer; Yong Yang; Jie Zhai; Chungwei Du; Peggy Hsieh; Manju M Hingorani; Dorothy A Erie
Journal:  J Biol Chem       Date:  2008-10-14       Impact factor: 5.157

9.  Mechanism of formation of a toroid around DNA by the mismatch sensor protein.

Authors:  Shivlee Nirwal; Dhananjaya S Kulkarni; Amit Sharma; Desirazu N Rao; Deepak T Nair
Journal:  Nucleic Acids Res       Date:  2018-01-09       Impact factor: 16.971

10.  Vanadate inhibits the ATPase activity and DNA binding capability of bacterial MutS. A structural model for the vanadate-MutS interaction at the Walker A motif.

Authors:  Roberto J Pezza; Marcos A Villarreal; Guillermo G Montich; Carlos E Argaraña
Journal:  Nucleic Acids Res       Date:  2002-11-01       Impact factor: 16.971
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