Literature DB >> 11179875

The LDL receptor gene family: signaling functions during development.

B W Howell1, J Herz.   

Abstract

The traditional views regarding the biological functions of the low-density lipoprotein (LDL) receptor gene family have been revisited recently with new evidence that at least some of the members of this receptor family act as signal-transduction molecules. Known for their role in endocytosis, particularly of their namesake the LDLs, and for their role in the prevention of atherosclerosis, these receptors belong to an ancient family with numerous ligands, effector molecules and functions. Recent evidence implicates this family of receptors in diverse signaling pathways, long-term potentiation and neuronal degeneration.

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Year:  2001        PMID： 11179875     DOI： 10.1016/s0959-4388(00)00176-8

Source DB:  PubMed          Journal:  Curr Opin Neurobiol        ISSN： 0959-4388            Impact factor:   6.627


  13 in total

1.  Sequence and structure of human rhinoviruses reveal the basis of receptor discrimination.

Authors:  Marketa Vlasak; Soile Blomqvist; Tapani Hovi; Elizabeth Hewat; Dieter Blaas
Journal:  J Virol       Date:  2003-06       Impact factor: 5.103

2.  Variations of very low-density lipoprotein receptor subtype expression in gastrointestinal adenocarcinoma cells with various differentiations.

Authors:  Tao Chen; Fan Wu; Feng-Ming Chen; Jun Tian; Shen Qu
Journal:  World J Gastroenterol       Date:  2005-05-14       Impact factor: 5.742

3.  Immunohistochemical localization of low density lipoprotein receptor-related protein 1 and alpha(2)-Macroglobulin in retinal and choroidal tissue of proliferative retinopathies.

Authors:  P F Barcelona; J D Luna; G A Chiabrando; C P Juarez; I A Bhutto; T Baba; D S McLeod; M C Sánchez; G A Lutty
Journal:  Exp Eye Res       Date:  2010-06-01       Impact factor: 3.467

4.  Dual roles for the Dab2 adaptor protein in embryonic development and kidney transport.

Authors:  Shelli M Morris; Michelle D Tallquist; Charles O Rock; Jonathan A Cooper
Journal:  EMBO J       Date:  2002-04-02       Impact factor: 11.598

5.  Protein multifunctionality: principles and mechanisms.

Authors:  Joseph Z Zaretsky; Daniel H Wreschner
Journal:  Transl Oncogenomics       Date:  2008-05-15

6.  The PX-domain protein SNX17 interacts with members of the LDL receptor family and modulates endocytosis of the LDL receptor.

Authors:  Walter Stockinger; Beate Sailler; Vera Strasser; Burgi Recheis; Daniela Fasching; Larissa Kahr; Wolfgang J Schneider; Johannes Nimpf
Journal:  EMBO J       Date:  2002-08-15       Impact factor: 11.598

7.  Lipoprotein receptors and a disabled family cytoplasmic adaptor protein regulate EGL-17/FGF export in C. elegans.

Authors:  Darren M Kamikura; Jonathan A Cooper
Journal:  Genes Dev       Date:  2003-11-15       Impact factor: 11.361

8.  Bovine apolipoprotein B-100 is a dominant immunogen in therapeutic cell populations cultured in fetal calf serum in mice and humans.

Authors:  Norihisa Sakamoto; Kazuhide Tsuji; Linda M Muul; Ann M Lawler; Emanuel F Petricoin; Fabio Candotti; Julia A Metcalf; Jorge A Tavel; H Clifford Lane; Walter J Urba; Bernard A Fox; Ajit Varki; Joan K Lunney; Amy S Rosenberg
Journal:  Blood       Date:  2007-03-29       Impact factor: 22.113

9.  Boca-dependent maturation of beta-propeller/EGF modules in low-density lipoprotein receptor proteins.

Authors:  Joaquim Culi; Timothy A Springer; Richard S Mann
Journal:  EMBO J       Date:  2004-03-11       Impact factor: 11.598

10.  CTNNB1, AXIN1 and APC expression analysis of different medulloblastoma variants.

Authors:  Roseli da Silva; Suely K N Marie; Miyuki Uno; Hamilton Matushita; Alda Wakamatsu; Sergio Rosemberg; Sueli M Oba-Shinjo
Journal:  Clinics (Sao Paulo)       Date:  2013       Impact factor: 2.365
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