Literature DB >> 11179870

The midbrain--hindbrain boundary organizer.

M Rhinn1, M Brand.   

Abstract

Cell fate in the cephalic neural primordium is controlled by an organizer located at the midbrain-hindbrain boundary. Studies in chick, mouse and zebrafish converge to show that mutually repressive interactions between homeodomain transcription factors of the Otx and Gbx class position this organizer in the neural primordium. Once positioned, independent signaling pathways converge in their activity to drive organizer function. Fibroblast growth factors secreted from the organizer are necessary for, and sufficient to mimic, organizer activity in patterning the midbrain and anterior hindbrain, and are tightly controlled by feedback inhibition.

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Year:  2001        PMID： 11179870     DOI： 10.1016/s0959-4388(00)00171-9

Source DB:  PubMed          Journal:  Curr Opin Neurobiol        ISSN： 0959-4388            Impact factor:   6.627


  69 in total

1.  Hes1 and Hes3 regulate maintenance of the isthmic organizer and development of the mid/hindbrain.

Authors:  H Hirata; K Tomita; Y Bessho; R Kageyama
Journal:  EMBO J       Date:  2001-08-15       Impact factor: 11.598

2.  Hedgehog and Fgf signaling pathways regulate the development of tphR-expressing serotonergic raphe neurons in zebrafish embryos.

Authors:  H Teraoka; C Russell; J Regan; A Chandrasekhar; M L Concha; R Yokoyama; K Higashi; M Take-Uchi; W Dong; T Hiraga; N Holder; S W Wilson
Journal:  J Neurobiol       Date:  2004-09-05

3.  Temporally induced Nurr1 can induce a non-neuronal dopaminergic cell type in embryonic stem cell differentiation.

Authors:  Kai-Christian Sonntag; Rabi Simantov; Kwang-Soo Kim; Ole Isacson
Journal:  Eur J Neurosci       Date:  2004-03       Impact factor: 3.386

Review 4.  MicroRNA-9: functional evolution of a conserved small regulatory RNA.

Authors:  Yeliz Yuva-Aydemir; Alfred Simkin; Eduardo Gascon; Fen-Biao Gao
Journal:  RNA Biol       Date:  2011-07-01       Impact factor: 4.652

5.  Genomic sequence and spatiotemporal expression comparison of zebrafish mbx1 and its paralog, mbx2.

Authors:  Lou Chang; Brian Khoo; Loksum Wong; Vincent Tropepe
Journal:  Dev Genes Evol       Date:  2006-05-30       Impact factor: 0.900

6.  Multiple zebrafish atoh1 genes specify a diversity of neuronal types in the zebrafish cerebellum.

Authors:  Chelsea U Kidwell; Chen-Ying Su; Masahiko Hibi; Cecilia B Moens
Journal:  Dev Biol       Date:  2018-03-13       Impact factor: 3.582

7.  Xenopus Nkx6.1 and Nkx6.2 are required for mid-hindbrain boundary development.

Authors:  Pengcheng Ma; Yingjie Xia; Li Ma; Shuhua Zhao; Bingyu Mao
Journal:  Dev Genes Evol       Date:  2013-02-20       Impact factor: 0.900

8.  Generation of serotonin neurons from human pluripotent stem cells.

Authors:  Jianfeng Lu; Xuefei Zhong; Huisheng Liu; Ling Hao; Cindy Tzu-Ling Huang; Mohammad Amin Sherafat; Jeffrey Jones; Melvin Ayala; Lingjun Li; Su-Chun Zhang
Journal:  Nat Biotechnol       Date:  2015-12-14       Impact factor: 54.908

9.  Duplicate dmbx1 genes regulate progenitor cell cycle and differentiation during zebrafish midbrain and retinal development.

Authors:  Loksum Wong; Cameron J Weadick; Claire Kuo; Belinda S W Chang; Vincent Tropepe
Journal:  BMC Dev Biol       Date:  2010-09-22       Impact factor: 1.978

10.  Zebrafish gbx1 refines the midbrain-hindbrain boundary border and mediates the Wnt8 posteriorization signal.

Authors:  Muriel Rhinn; Klaus Lun; Reiner Ahrendt; Michaela Geffarth; Michael Brand
Journal:  Neural Dev       Date:  2009-04-02       Impact factor: 3.842
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