OBJECTIVE: To determine the value of surgical closure of atrial septal defects in patients over 40 years of age. METHODS: Retrospective analysis of 76 patients (63 women, 13 men), age range 40-62 years (mean (SD) 45.8 (5.1) years), who underwent surgical repair of atrial septal defect. Pre- and postoperative clinical status (New York Heart Association (NYHA) functional class) was assessed, and ECG, x ray, and echocardiographic investigations performed. Follow up was between 1 and 17 years. RESULTS: One operative and one late death occurred during the study period. Before operation, 47 patients (61.8%) were in NYHA functional classes III and IV. After operation, 61 patients (82.4%) were in classes I and II. Four patients had atrial fibrillation before surgery versus nine after surgery. Before operation, 52 patients had intensified pulmonary vascularity compared with only seven after operation. Echocardiographic examination showed a significant reduction in right ventricular dimension (4.10 (0.91) v 2.95 (0.36) cm, p < 0.001). No residual intracardiac shunts were identified on echocardiographic follow up. CONCLUSIONS: Surgical closure of atrial septal defects in patients over 40 years old can improve their clinical status and prevent right ventricular dilatation and insufficiency.
OBJECTIVE: To determine the value of surgical closure of atrial septal defects in patients over 40 years of age. METHODS: Retrospective analysis of 76 patients (63 women, 13 men), age range 40-62 years (mean (SD) 45.8 (5.1) years), who underwent surgical repair of atrial septal defect. Pre- and postoperative clinical status (New York Heart Association (NYHA) functional class) was assessed, and ECG, x ray, and echocardiographic investigations performed. Follow up was between 1 and 17 years. RESULTS: One operative and one late death occurred during the study period. Before operation, 47 patients (61.8%) were in NYHA functional classes III and IV. After operation, 61 patients (82.4%) were in classes I and II. Four patients had atrial fibrillation before surgery versus nine after surgery. Before operation, 52 patients had intensified pulmonary vascularity compared with only seven after operation. Echocardiographic examination showed a significant reduction in right ventricular dimension (4.10 (0.91) v 2.95 (0.36) cm, p < 0.001). No residual intracardiac shunts were identified on echocardiographic follow up. CONCLUSIONS: Surgical closure of atrial septal defects in patients over 40 years old can improve their clinical status and prevent right ventricular dilatation and insufficiency.
Authors: J G Murphy; B J Gersh; M D McGoon; D D Mair; C J Porter; D M Ilstrup; D C McGoon; F J Puga; J W Kirklin; G K Danielson Journal: N Engl J Med Date: 1990-12-13 Impact factor: 91.245
Authors: S Schroeder; A F Kopp; A Baumbach; A Kuettner; C Georg; B Ohnesorge; C Herdeg; C D Claussen; K R Karsch Journal: Heart Date: 2001-05 Impact factor: 5.994
Authors: Kyoung-Min Park; Jin Kyung Hwang; Kwang Jin Chun; Seung-Jung Park; Young Keun On; June Soo Kim; Seung Woo Park; I-Seok Kang; Jinyoung Song; June Huh Journal: Medicine (Baltimore) Date: 2016-08 Impact factor: 1.889