| Literature DB >> 11178956 |
M Subbarayan1, S J Shetty, T S Srivastava, O P Noronha, A M Samuel, H Mukhtar.
Abstract
We have synthesized two water soluble dendritic porphyrins, termed DP1 and DP2 and have successfully radiolabeled them with 99mTc. These 99mTc-labeled porphyrins were administered to C6-glioma tumor bearing Wistar rats and scintiimaging and biodistribution studies were carried out. Tumor to muscle ratios of DP1 and DP2 were 8.0 and 9.7, respectively. These molecules may have potential for tumor imaging and diagnosis and may even prove useful as photosensitizers in photodynamic therapy applications.Entities:
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Year: 2001 PMID： 11178956 DOI： 10.1006/bbrc.2001.4289
Source DB: PubMed Journal: Biochem Biophys Res Commun ISSN： 0006-291X Impact factor: 3.575