Literature DB >> 11178818

Kinetic resolution of allylic alcohols using a chiral phosphine catalyst.

E Vedejs1, J A MacKay.   

Abstract

[reaction: see text] The kinetic resolution of racemic allylic alcohols 3, 6, and 12--17 has been explored using the PBO catalyst 7 for activation of isobutyric anhydride. Trisubstituted allylic alcohols (12--15; 17) are the best substrates and react with an enantioselectivity of s = 32--82 at -40 degrees C.

Entities:  

Year:  2001        PMID： 11178818     DOI： 10.1021/ol006923g

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  5 in total

1.  Kinetic resolution of secondary alcohols using amidine-based catalysts.

Authors:  Ximin Li; Hui Jiang; Eric W Uffman; Lei Guo; Yuhua Zhang; Xing Yang; Vladimir B Birman
Journal:  J Org Chem       Date:  2012-02-09       Impact factor: 4.354

2.  Enantioselective TADMAP-catalyzed carboxyl migration reactions for the synthesis of stereogenic quaternary carbon.

Authors:  Scott A Shaw; Pedro Aleman; Justin Christy; Jeff W Kampf; Porino Va; Edwin Vedejs
Journal:  J Am Chem Soc       Date:  2006-01-25       Impact factor: 15.419

3.  One-pot odourless synthesis of thioesters via in situ generation of thiobenzoic acids using benzoic anhydrides and thiourea.

Authors:  Mohammad Abbasi; Reza Khalifeh
Journal:  Beilstein J Org Chem       Date:  2015-07-28       Impact factor: 2.883

4.  Isothiourea-Catalysed Acylative Kinetic Resolution of Aryl-Alkenyl (sp2 vs. sp2 ) Substituted Secondary Alcohols.

Authors:  Stefania F Musolino; O Stephen Ojo; Nicholas J Westwood; James E Taylor; Andrew D Smith
Journal:  Chemistry       Date:  2016-11-30       Impact factor: 5.236

5.  Highly Efficient Kinetic Resolution of Aryl-Alkenyl Alcohols by Ru-Catalyzed Hydrogen Transfer.

Authors:  Yipeng You; Ming Yu Jin; Guanyu Tao; Xiangyou Xing
Journal:  Molecules       Date:  2021-12-10       Impact factor: 4.411
  5 in total

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