PURPOSE: The purpose of this work was to compare, using quantitative CT (QCT), vertebral bone mineral density (BMD) in the cervical, thoracic, and lumbar spine in healthy volunteers. METHOD: QCT of the vertebral bodies of C2, C5, T12, and L4 was performed on 50 healthy volunteers (25 women, 25 men; mean age 31.7 years). Trabecular BMD analysis was performed at each level. RESULTS: Mean BMDs (mg/cm3 calcium hydroxyapatite) for women and men were highest at C5 (BMD women/men 341.6/300.6 mg/cm3) and C2 (297.2/269.6 mg/cm3) and lowest at T12 (193.1/184.9 mg/cm3) and L4 (186.2/180.1 mg/cm3). The BMD of C2 was statistically significantly different from that of C5, T12, and L4 (p < 0.0001) for both genders. Also, the BMD of C5 differed significantly from that of T12 and L4 (p < 0.0001). The BMD of C5 showed significant gender differences (p = 0.002). Correlation coefficient showed a strong correlation between the BMD of T12 and L4 for both genders (women, r = 0.67; men, r = 0.90). CONCLUSION: Trabecular BMD of C2 and C5 measured by QCT is significantly higher than trabecular BMD of T12 and L4 in nonosteoporotic volunteers of both genders.
PURPOSE: The purpose of this work was to compare, using quantitative CT (QCT), vertebral bone mineral density (BMD) in the cervical, thoracic, and lumbar spine in healthy volunteers. METHOD: QCT of the vertebral bodies of C2, C5, T12, and L4 was performed on 50 healthy volunteers (25 women, 25 men; mean age 31.7 years). Trabecular BMD analysis was performed at each level. RESULTS: Mean BMDs (mg/cm3 calcium hydroxyapatite) for women and men were highest at C5 (BMD women/men 341.6/300.6 mg/cm3) and C2 (297.2/269.6 mg/cm3) and lowest at T12 (193.1/184.9 mg/cm3) and L4 (186.2/180.1 mg/cm3). The BMD of C2 was statistically significantly different from that of C5, T12, and L4 (p < 0.0001) for both genders. Also, the BMD of C5 differed significantly from that of T12 and L4 (p < 0.0001). The BMD of C5 showed significant gender differences (p = 0.002). Correlation coefficient showed a strong correlation between the BMD of T12 and L4 for both genders (women, r = 0.67; men, r = 0.90). CONCLUSION: Trabecular BMD of C2 and C5 measured by QCT is significantly higher than trabecular BMD of T12 and L4 in nonosteoporotic volunteers of both genders.
Authors: Mary Lucy Marques; Nuno Pereira da Silva; Desirée van der Heijde; Monique Reijnierse; Xenofon Baraliakos; Juergen Braun; Floris A van Gaalen; Sofia Ramiro Journal: RMD Open Date: 2022-06
Authors: Yi-Xiang J Wang; James F Griffith; Hua Zhou; Kai Chow Choi; Vivian W Y Hung; David K W Yeung; Ling Qin; Anil T Ahuja Journal: Eur Radiol Date: 2008-10-29 Impact factor: 5.315
Authors: F Johannesdottir; B Allaire; D L Kopperdahl; T M Keaveny; S Sigurdsson; M A Bredella; D E Anderson; E J Samelson; D P Kiel; V G Gudnason; M L Bouxsein Journal: Osteoporos Int Date: 2020-08-03 Impact factor: 4.507