Literature DB >> 11175802

Chemokines and disease.

C Gerard1, B J Rollins.   

Abstract

We examine here several diseases that are associated with inappropriate activation of the chemokine network. Detailed comment has been restricted to pathological states for which there are compelling data either from clinical observations or animal models. These include cardiovascular disease, allergic inflammatory disease, transplantation, neuroinflammation, cancer and HIV-associated disease. Discussion focuses on therapeutic directions in which the rapidly evolving chemokine field appears to be headed.

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Year:  2001        PMID: 11175802     DOI: 10.1038/84209

Source DB:  PubMed          Journal:  Nat Immunol        ISSN: 1529-2908            Impact factor:   25.606


  342 in total

1.  A rapid and efficient way to obtain modified chemokines for functional and biophysical studies.

Authors:  Samantha J Allen; Damon J Hamel; Tracy M Handel
Journal:  Cytokine       Date:  2011-05-31       Impact factor: 3.861

2.  Impairment of leukocyte trafficking in a murine pleuritis model by IL-4 and IL-10.

Authors:  Jay S Fine; Alberto Rojas-Triana; James V Jackson; Laura W Engstrom; Gregory S Deno; Daniel J Lundell; Loretta A Bober
Journal:  Inflammation       Date:  2003-08       Impact factor: 4.092

Review 3.  Chemokines and glial cells: a complex network in the central nervous system.

Authors:  Elena Ambrosini; Francesca Aloisi
Journal:  Neurochem Res       Date:  2004-05       Impact factor: 3.996

Review 4.  Renin-angiotensin system blockers and modulation of radiation-induced brain injury.

Authors:  M E Robbins; W Zhao; M A Garcia-Espinosa; D I Diz
Journal:  Curr Drug Targets       Date:  2010-11       Impact factor: 3.465

5.  Chemokines and their receptors in intracerebral hemorrhage.

Authors:  Yao Yao; Stella E Tsirka
Journal:  Transl Stroke Res       Date:  2012-04-03       Impact factor: 6.829

6.  Dynamics of M1 macrophages in oral mucosal lesions during the development of acute graft-versus-host disease in rats.

Authors:  K Seno; M Yasunaga; H Kajiya; K Izaki-Hagio; H Morita; M Yoneda; T Hirofuji; J Ohno
Journal:  Clin Exp Immunol       Date:  2017-09-28       Impact factor: 4.330

Review 7.  Chemokine receptor antagonists: overcoming developmental hurdles.

Authors:  Richard Horuk
Journal:  Nat Rev Drug Discov       Date:  2008-12-12       Impact factor: 84.694

8.  In vivo ablation of plasmacytoid dendritic cells inhibits autoimmunity through expansion of myeloid-derived suppressor cells.

Authors:  Marianna Ioannou; Themis Alissafi; Louis Boon; Dimitrios Boumpas; Panayotis Verginis
Journal:  J Immunol       Date:  2013-02-04       Impact factor: 5.422

9.  CCR6 regulation of the actin cytoskeleton orchestrates human beta defensin-2- and CCL20-mediated restitution of colonic epithelial cells.

Authors:  Rebecca A Vongsa; Noah P Zimmerman; Michael B Dwinell
Journal:  J Biol Chem       Date:  2009-02-20       Impact factor: 5.157

10.  The chemokine receptor CCR5 plays a role in post-traumatic cartilage loss in mice, but does not affect synovium and bone.

Authors:  K Takebe; M F Rai; E J Schmidt; L J Sandell
Journal:  Osteoarthritis Cartilage       Date:  2014-12-09       Impact factor: 6.576

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