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Literature DB >> 1117486

Characterization of the inhomogeneous DNA in virions of bacteriophage Mu by DNA reannealing kinetics.

Abstract

The DNA of bacteriophage Mu has been studied to characterize a region of inhomogeneous sequence that occurs at one end of the molecule. The kinetics of reassocation of tracer amounts of labeled host DNA in the presence of Mu DNA show that Mu DNA contains a complete selection of host sequences. These host sequences are shown to be covalently attached to phage-specific sequences and are present at a concentration that accounts for the inhomogeneity observed in the electron microscope. The significance and possible function of the host DNA attachment is discussed.

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Year: 1975 PMID： 1117486 PMCID： PMC354517

Source DB: PubMed Journal: J Virol ISSN： 0022-538X Impact factor: 5.103

18 in total

6. Mechanism of phage Mu-1 integration: nalidixic acid treatment causes clustering of Mu-1-induced mutations near replication origin.

Authors: L Paolozzi; R Jucker; E Calef
Journal: Proc Natl Acad Sci U S A Date: 1978-10 Impact factor: 11.205

Characterization of the inhomogeneous DNA in virions of bacteriophage Mu by DNA reannealing kinetics.

1. HOMOLOGY BETWEEN BACTERIOPHAGE LAMBDA DNA AND E. COLI DNA.

2. Genetic study of prophage excision with a temperature inducible mutant of Mu-1.

3. Asymmetric transcription of bacteriophage Mu-1.

4. Heteroduplex structures of bacteriophage Mu DNA.

5. Origin and sequence of chromosome replication in Escherichia coli.

6. Transduction by bacteriophage MU-1.

7. Prophage deletion mapping of bacteriophage Mu-1.

8. Nucleotide sequence determination of bacteriophage T4 leucine transfer ribonucleic acid.

9. Quantitation of Simian virus 40 sequences in African green monkey, mouse and virus-transformed cell genomes.

10. Isolation of heterogeneous circular DNA from induced lysogens of bacteriophage Mu-1.

1. Influence of insertions on packaging of host sequences covalently linked to bacteriophage Mu DNA.

2. The origin of the DNA in transducing particles of bacteriophage Mu. Density gradient analyses of intact phages.

Review 3. Head morphogenesis of complex double-stranded deoxyribonucleic acid bacteriophages.

4. Early events in the replication of Mu prophage DNA.

5. Replication of prophage P1 during the cell cycle of Escherichia coli.

6. Mechanism of phage Mu-1 integration: nalidixic acid treatment causes clustering of Mu-1-induced mutations near replication origin.

7. Transfection of Escherichia coli by Mu DNA.

8. Transduction of multi-copy plasmid pBR322 by bacteriophage Mu.

9. The products of gene A of the related phages Mu and D108 differ in their specificities.

10. DNA methyltransferase-dependent transcription of the phage Mu mom gene.