Literature DB >> 11174731

Operation for acute type A aortic dissection in octogenarians: is it justified?

E Neri1, T Toscano, M Massetti, G Capannini, E Carone, E Tucci, F Diciolla, S Scolletta, R Morello, C Sassi.   

Abstract

BACKGROUND: With the progressive aging of Western populations, cardiac surgeons are faced with treating an increasing number of elderly patients. Controversy exists as to whether the expenditure of health care resources on the growing elderly populations represents a cost-effective approach to resource management. The potential to avoid surgery in patients with little chance of survival and poor quality of life would spare unnecessary suffering, reduce operative mortality, and enhance the use of scarce resources.
METHODS: We reviewed the records of 24 consecutive patients aged 80 years or older (mean age 83 years, range 80-93 years) who underwent operations for acute type A dissection from 1985 through 1999. No patient with acute type A dissection was refused surgery because of age or concomitant disease. Seventeen patients were men. Preoperatively, none of the patients was moribund, although 66% had hemodynamic instability and 41% experienced cerebral ischemia. All patients had one or more associated pathologic conditions. Hospital mortality and morbidity models, based on our overall experience with 197 patients operated on for acute type A aortic dissection during the period of the study, were developed by means of multivariate logistic regression with preoperative and intraoperative variables used as independent predictors of outcome.
RESULTS: Overall hospital mortality was 83%. Intraoperative mortality was 33%. All patients who survived the operation had one or more postoperative complications. Mean hospital stay was 37 days with a total of 314 days in the intensive care unit (average 19 days, median 17 days). None of the survivors (4 patients) discharged from the hospital was able to function independently and their survival at 6 months was 0%. Statistical analysis of the overall experience with operations for type A acute aortic dissection confirmed that age in excess of 80 years is the most important independent patient risk factor associated with 30-day mortality and morbidity.
CONCLUSIONS: Operations for acute type A dissection performed on octogenarians involve increased hospital mortality and morbidity. Short-term survival is unfavorable and is associated with a poor quality of life. Without additional corroborative studies to endorse the present findings, the use of age as a parameter to limit access of patients to expensive medical resources remains an unsubstantiated concept. In the context of acute type A aortic dissection, however, the hypothesis that older patients should be denied such a complicated surgical intervention to conserve resources is supported by the presented data.

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Year:  2001        PMID: 11174731     DOI: 10.1067/mtc.2001.112205

Source DB:  PubMed          Journal:  J Thorac Cardiovasc Surg        ISSN: 0022-5223            Impact factor:   5.209


  19 in total

1.  Analysis of early and long-term outcomes of acute type A aortic dissection according to the new international aortic arch surgery study group recommendations.

Authors:  Andrea Colli; Massimiliano Carrozzini; Marco Galuppo; Marina Comisso; Francesca Toto; Dario Gregori; Gino Gerosa
Journal:  Heart Vessels       Date:  2015-11-17       Impact factor: 2.037

Review 2.  Emergent aortic surgery in octogenarians: is the advanced age a contraindication?

Authors:  Mario Castaño; Javier Gualis; Jose M Martínez-Comendador; Elio Martín; Pasquale Maiorano; Laura Castillo
Journal:  J Thorac Dis       Date:  2017-05       Impact factor: 2.895

3.  [German Registry for Acute Aortic Dissection Type A (GERAADA): initial results].

Authors:  L O Conzelmann; T Krüger; I Hoffmann; B Rylski; J Easo; M Oezkur; K Kallenbach; O Dapunt; M Karck; E Weigang
Journal:  Herz       Date:  2011-09       Impact factor: 1.443

4.  Stable haemodynamics associated with no significant electrocardiogram abnormalities is a good prognostic factor of survival for acute type A aortic dissection repair.

Authors:  Tsu-Ming Chien; Wei-Yu Li; Hao Wen; Jiann-Woei Huang; Chong-Chao Hsieh; Huai-Min Chen; Chaw-Chi Chiu; Ying-Fu Chen
Journal:  Interact Cardiovasc Thorac Surg       Date:  2012-11-19

Review 5.  Aortic dissections in the elderly: ethical dilemmas of treatment.

Authors:  Anthony L Estrera; Hazim J Safi
Journal:  Tex Heart Inst J       Date:  2012

6.  Acute type a aortic dissection: for further improvement of outcomes.

Authors:  Kazumasa Orihashi
Journal:  Ann Vasc Dis       Date:  2012

Review 7.  Evolution of surgical therapy for Stanford acute type A aortic dissection.

Authors:  Peter Chiu; D Craig Miller
Journal:  Ann Cardiothorac Surg       Date:  2016-07

8.  Postoperative Outcome of High-Risk Octogenarians Undergoing Cardiac Surgery: A Multicenter Observational Retrospective Study.

Authors:  Michal Porizka; Jan Kunstyr; Tomas Vanek; Michal Nejedly; Jana Buckova; Jiri Mokrejs; Frantisek Mosna
Journal:  Ann Thorac Cardiovasc Surg       Date:  2017-05-24       Impact factor: 1.520

9.  Emergency surgery results in life-threatening thoracic aortic disease.

Authors:  Yoshito Kawachi; Yoshihiro Toshima; Atsuhiro Nakashima; Kouichi Arinaga; Isao Komesu
Journal:  Jpn J Thorac Cardiovasc Surg       Date:  2002-04

10.  Quality of life after replacement of the ascending aorta in patients with true aneurysms.

Authors:  Folke Lohse; Nora Lang; Wolfgang Schiller; Wilhelm Roell; Oliver Dewald; Claus-Juergen Preusse; Armin Welz; Christoph Schmitz
Journal:  Tex Heart Inst J       Date:  2009
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