Literature DB >> 11173833

TSPY variants in six loci on the human Y chromosome.

F Dechend1, G Williams, B Skawran, S Schubert, M Krawczak, C Tyler-Smith, J Schmidtke.   

Abstract

We have studied the structure, organization, and evolution of the human TSPY gene family by mapping three sequence variants identified through RT-PCR analysis onto genomic clones derived from two different YAC contigs. TSPY gene family members occur in at least six locations on the human Y chromosome, and each cluster contains a unique combination of variants. Our data further suggest that an 18-bp tandem duplication found in TSPY exon 1 originated from an unequal sister chromatid exchange between two tandemly arranged TSPY clusters. Copyright 2001 S. Karger AG, Basel

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Year:  2000        PMID： 11173833     DOI： 10.1159/000056821

Source DB:  PubMed          Journal:  Cytogenet Cell Genet        ISSN： 0301-0171


  8 in total

1.  Characterization of a human TSPY promoter.

Authors:  Britta Skawran; Stephanie Schubert; Frank Dechend; Jörg Vervoorts; Karim Nayernia; Bernhard Lüscher; Jörg Schmidtke
Journal:  Mol Cell Biochem       Date:  2005-08       Impact factor: 3.396

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Journal:  Mol Biol Rep       Date:  2020-01-25       Impact factor: 2.316

Review 3.  Testicular cancer: biology and biomarkers.

Authors:  Leendert H J Looijenga; Hans Stoop; Katharina Biermann
Journal:  Virchows Arch       Date:  2014-02-01       Impact factor: 4.064

4.  W-derived BAC probes as a new tool for identification of the W chromosome and its aberrations in Bombyx mori.

Authors:  Ken Sahara; Atsuo Yoshido; Naoko Kawamura; Akio Ohnuma; Hiroaki Abe; Kazuei Mita; Toshikazu Oshiki; Toru Shimada; Shin-Ichiro Asano; Hisanori Bando; Yuji Yasukochi
Journal:  Chromosoma       Date:  2003-06-24       Impact factor: 4.316

5.  The Y-encoded TSPY protein: a significant marker potentially plays a role in the pathogenesis of testicular germ cell tumors.

Authors:  Yunmin Li; Z Laura Tabatabai; Tin-Lap Lee; Shingo Hatakeyama; Chikara Ohyama; Wai-Yee Chan; Leendert H J Looijenga; Yun-Fai Chris Lau
Journal:  Hum Pathol       Date:  2007-05-22       Impact factor: 3.466

6.  TSPY potentiates cell proliferation and tumorigenesis by promoting cell cycle progression in HeLa and NIH3T3 cells.

Authors:  Shane W Oram; Xing Xing Liu; Tin-Lap Lee; Wai-Yee Chan; Yun-Fai Chris Lau
Journal:  BMC Cancer       Date:  2006-06-09       Impact factor: 4.430

7.  An Exceptional Gene: Evolution of the TSPY Gene Family in Humans and Other Great Apes.

Authors:  Yali Xue; Chris Tyler-Smith
Journal:  Genes (Basel)       Date:  2011-01-10       Impact factor: 4.096

8.  Transgenic Mouse Studies to Understand the Regulation, Expression and Function of the Testis-Specific Protein Y-Encoded (TSPY) Gene.

Authors:  Stephanie Schubert; Jörg Schmidtke
Journal:  Genes (Basel)       Date:  2010-08-18       Impact factor: 4.096
  8 in total

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