Literature DB >> 11173400

10-Deacetyl baccatin III dimethyl sulfoxide disolvate.

J K Harper 1, N K Dalley , A E Mulgrew , F G West , D M Grant .   

Abstract

The title compound, C29H36O10.2C2H6OS, forms a monoclinic crystal containing two hydrogen-bonded dimethyl sulfoxide molecules per 10-deacetyl baccatin III. The lattice is further stabilized by two additional hydrogen bonds and a dipole-dipole interaction. A comparison of 10-deacetyl baccatin III with the structurally similar docetaxel reveals differences primarily in the benzoyl moiety, while comparisons to baccatin III identify relative differences principally in the cyclooctane- and cyclohexane-ring conformations.

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Year:  2001        PMID: 11173400     DOI: 10.1107/s0108270100011781

Source DB:  PubMed          Journal:  Acta Crystallogr C        ISSN: 0108-2701            Impact factor:   1.172


  1 in total

1.  Concomitant pseudopolymorphs of 10-deacetyl baccatin III.

Authors:  Lakshmi Kumar Tatini; N Someswara Rao; Muzaffar Khan; Krishna Sumanth Peraka; K V S R Krishna Reddy
Journal:  AAPS PharmSciTech       Date:  2013-03-13       Impact factor: 3.246

  1 in total

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