| Literature DB >> 11173400 |
J K Harper 1, N K Dalley , A E Mulgrew , F G West , D M Grant .
Abstract
The title compound, C29H36O10.2C2H6OS, forms a monoclinic crystal containing two hydrogen-bonded dimethyl sulfoxide molecules per 10-deacetyl baccatin III. The lattice is further stabilized by two additional hydrogen bonds and a dipole-dipole interaction. A comparison of 10-deacetyl baccatin III with the structurally similar docetaxel reveals differences primarily in the benzoyl moiety, while comparisons to baccatin III identify relative differences principally in the cyclooctane- and cyclohexane-ring conformations.Entities:
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Year: 2001 PMID: 11173400 DOI: 10.1107/s0108270100011781
Source DB: PubMed Journal: Acta Crystallogr C ISSN: 0108-2701 Impact factor: 1.172