Literature DB >> 11173305

Device for sterile online measurement of the oxygen transfer rate in shaking flasks.

T Anderlei1, J Büchs.   

Abstract

The oxygen transfer rate (OTR) is the most suitable measurable parameter to quantify the physiological state of a culture of aerobic microorganisms since most metabolic activities depend on oxygen consumption. Online measurement of the oxygen transfer rate in stirred bioreactors is state of the art although technically difficult. However, the online determination of the oxygen transfer rate in shaking bioreactors under sterile conditions has not been possible until recently. A newly developed measuring device eliminates this deficit. Extremely useful information about cultivating conditions and the physiological state of microorganisms can be gained in early stages of research and bioprocess development from many reactors operated in parallel.

Entities:  

Year:  2001        PMID： 11173305     DOI： 10.1016/s1369-703x(00)00116-9

Source DB:  PubMed          Journal:  Biochem Eng J        ISSN： 1369-703X            Impact factor:   3.978


  61 in total

1.  The oxygen transfer rate as key parameter for the characterization of Hansenula polymorpha screening cultures.

Authors:  Christoph Stöckmann; Ulrike Maier; Tibor Anderlei; Christof Knocke; Gerd Gellissen; Jochen Büchs
Journal:  J Ind Microbiol Biotechnol       Date:  2003-10-28       Impact factor: 3.346

2.  An experimental comparison of respiration measuring techniques in fermenters and shake flasks: exhaust gas analyzer vs. RAMOS device vs. respirometer.

Authors:  Juri M Seletzky; Ute Noack; Sebastian Hahn; Arnd Knoll; Ghassem Amoabediny; Jochen Büchs
Journal:  J Ind Microbiol Biotechnol       Date:  2006-09-26       Impact factor: 3.346

3.  Evidence for a key role of cytochrome bo3 oxidase in respiratory energy metabolism of Gluconobacter oxydans.

Authors:  Janine Richhardt; Bettina Luchterhand; Stephanie Bringer; Jochen Büchs; Michael Bott
Journal:  J Bacteriol       Date:  2013-07-12       Impact factor: 3.490

4.  Quantifying the sensitivity of G. oxydans ATCC 621H and DSM 3504 to osmotic stress triggered by soluble buffers.

Authors:  B Luchterhand; T Fischöder; A R Grimm; S Wewetzer; M Wunderlich; T Schlepütz; J Büchs
Journal:  J Ind Microbiol Biotechnol       Date:  2015-02-03       Impact factor: 3.346

5.  Influence of nitrogen source and pH value on undesired poly(γ-glutamic acid) formation of a protease producing Bacillus licheniformis strain.

Authors:  Lena Meissner; Kira Kauffmann; Timo Wengeler; Hitoshi Mitsunaga; Eiichiro Fukusaki; Jochen Büchs
Journal:  J Ind Microbiol Biotechnol       Date:  2015-07-08       Impact factor: 3.346

6.  High-throughput workflow for monitoring and mining bioprocess data and its application to inferring the physiological response of Escherichia coli to perturbations.

Authors:  Stéphanie Heux; Benjamin Philippe; Jean-Charles Portais
Journal:  Appl Environ Microbiol       Date:  2011-08-12       Impact factor: 4.792

7.  Poly(3-hydroxybutyrate) accumulation by Azotobacter vinelandii under different oxygen transfer strategies.

Authors:  Alvaro Díaz-Barrera; Viviana Urtuvia; Claudio Padilla-Córdova; Carlos Peña
Journal:  J Ind Microbiol Biotechnol       Date:  2018-10-24       Impact factor: 3.346

8.  Scale-up from microtiter plate to laboratory fermenter: evaluation by online monitoring techniques of growth and protein expression in Escherichia coli and Hansenula polymorpha fermentations.

Authors:  Frank Kensy; Christoph Engelbrecht; Jochen Büchs
Journal:  Microb Cell Fact       Date:  2009-12-22       Impact factor: 5.328

9.  Physiological relation between respiration activity and heterologous expression of selected benzoylformate decarboxylase variants in Escherichia coli.

Authors:  Thomas G Palmen; Jens Nieveler; Bettina Frölich; Wiltrud Treffenfeldt; Martina Pohl; Jochen Büchs
Journal:  Microb Cell Fact       Date:  2010-10-19       Impact factor: 5.328

10.  Magnetically remote-controlled optical sensor spheres for monitoring oxygen or pH.

Authors:  Günter Mistlberger; Klaus Koren; Sergey M Borisov; Ingo Klimant
Journal:  Anal Chem       Date:  2010-03-01       Impact factor: 6.986
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