Literature DB >> 11171212

The non-mevalonate isoprenoid biosynthesis of plants as a test system for drugs against malaria and pathogenic bacteria.

J Zeidler1, J Schwender, C Mueller, H K Lichtenthaler.   

Abstract

Two plant test systems are presented in the search for new inhibitors of the non-mevalonate isoprenoid pathway. A derivative of clomazone appears to be an inhibitor of the deoxyxylulose 5-phosphate/methylerythritol 4-phosphate (DOXP/MEP) pathway of isoprenoid formation.

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Year:  2000        PMID： 11171212

Source DB:  PubMed          Journal:  Biochem Soc Trans        ISSN： 0300-5127            Impact factor:   5.407


  13 in total

1.  Hartmut Lichtenthaler: an authority on chloroplast structure and isoprenoid biochemistry.

Authors:  Thomas D Sharkey
Journal:  Photosynth Res       Date:  2015-12-15       Impact factor: 3.573

2.  Vitamin B6 biosynthesis in higher plants.

Authors:  Marina Tambasco-Studart; Olca Titiz; Thomas Raschle; Gabriela Forster; Nikolaus Amrhein; Teresa B Fitzpatrick
Journal:  Proc Natl Acad Sci U S A       Date:  2005-09-12       Impact factor: 11.205

3.  Enhanced flux through the methylerythritol 4-phosphate pathway in Arabidopsis plants overexpressing deoxyxylulose 5-phosphate reductoisomerase.

Authors:  Lorenzo Carretero-Paulet; Albert Cairó; Patricia Botella-Pavía; Oscar Besumbes; Narciso Campos; Albert Boronat; Manuel Rodríguez-Concepción
Journal:  Plant Mol Biol       Date:  2006-08-29       Impact factor: 4.076

4.  Agrobacterium tumefaciens increases cytokinin production in plastids by modifying the biosynthetic pathway in the host plant.

Authors:  Hitoshi Sakakibara; Hiroyuki Kasahara; Nanae Ueda; Mikiko Kojima; Kentaro Takei; Shojiro Hishiyama; Tadao Asami; Kazunori Okada; Yuji Kamiya; Tomoyuki Yamaya; Shinjiro Yamaguchi
Journal:  Proc Natl Acad Sci U S A       Date:  2005-07-05       Impact factor: 11.205

5.  Identification of novel small molecule inhibitors of 4-diphosphocytidyl-2-C-methyl-D-erythritol (CDP-ME) kinase of Gram-negative bacteria.

Authors:  M Tang; S I Odejinmi; Y M Allette; H Vankayalapati; K Lai
Journal:  Bioorg Med Chem       Date:  2011-08-16       Impact factor: 3.641

6.  Effects of brassinazole, an inhibitor of brassinosteroid biosynthesis, on light- and dark-grown Chlorella vulgaris.

Authors:  Andrzej Bajguz; Tadao Asami
Journal:  Planta       Date:  2003-12-04       Impact factor: 4.116

7.  Formal Synthesis of 4-diphosphocytidyl-2-C-methyl D-erythritol From D-(+)-Arabitol.

Authors:  Sina I Odejinmi; Rafael G Rascon; Wyman Chen; Kent Lai
Journal:  Tetrahedron       Date:  2012-10-28       Impact factor: 2.457

8.  The plastidial 2-C-methyl-D-erythritol 4-phosphate pathway provides the isoprenyl moiety for protein geranylgeranylation in tobacco BY-2 cells.

Authors:  Esther Gerber; Andréa Hemmerlin; Michael Hartmann; Dimitri Heintz; Marie-Andrée Hartmann; Jérôme Mutterer; Manuel Rodríguez-Concepción; Albert Boronat; Alain Van Dorsselaer; Michel Rohmer; Dring N Crowell; Thomas J Bach
Journal:  Plant Cell       Date:  2009-01-09       Impact factor: 11.277

9.  Arabidopsis J-protein J20 delivers the first enzyme of the plastidial isoprenoid pathway to protein quality control.

Authors:  Pablo Pulido; Gabriela Toledo-Ortiz; Michael A Phillips; Louwrance P Wright; Manuel Rodríguez-Concepción
Journal:  Plant Cell       Date:  2013-10-08       Impact factor: 11.277

Review 10.  Thiamin (vitamin B1) biosynthesis and regulation: a rich source of antimicrobial drug targets?

Authors:  Qinglin Du; Honghai Wang; Jianping Xie
Journal:  Int J Biol Sci       Date:  2011-01-09       Impact factor: 6.580
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