Literature DB >> 11170686

Circumdatin G, a new alkaloid from the fungus Aspergillus ochraceus.

J Dai1, B K Carté, P J Sidebottom, A L Sek Yew, S Ng, Y Huang, M S Butler.   

Abstract

The crude extract of the broth of Aspergillus ochraceus was found to inhibit the final stage of polyprotein processing during hepatitis C virus replication. Bioassay-guided fractionation led to the isolation of the known compound mellein as the active component of the extract. Also isolated were circumdatin F and a new alkaloid, circumdatin G. The structure of circumdatin G was determined by spectroscopic analysis.

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Year:  2001        PMID： 11170686     DOI： 10.1021/np000381u

Source DB:  PubMed          Journal:  J Nat Prod        ISSN： 0163-3864            Impact factor:   4.050


  25 in total

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