Literature DB >> 11170659

Flavonol glycosides and steroidal saponins from the leaves of Cestrum nocturnum and their cytotoxicity.

Y Mimaki1, K Watanabe, Y Ando, C Sakuma, Y Sashida, S Furuya, H Sakagami.   

Abstract

Phytochemical analysis of the leaves of Cestrum nocturnum (Solanaceae) resulted in the isolation of two new flavonol glycosides (1, 2) and seven steroidal saponins (3-9), including four new ones (4, 6, 7, and 9). The structures of the new compounds were determined by spectroscopic analysis, including 2D NMR data, and the results of hydrolytic cleavage. Cytotoxic activities of the isolated compounds against human oral squamous cell carcinoma-(HSC-2) cells and normal human gingival fibroblasts are reported.

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Year:  2001        PMID: 11170659     DOI: 10.1021/np0003701

Source DB:  PubMed          Journal:  J Nat Prod        ISSN: 0163-3864            Impact factor:   4.050


  4 in total

1.  Network pharmacology-based study on apigenin present in the methanolic fraction of leaves extract of Cestrum nocturnum L. to uncover mechanism of action on hepatocellular carcinoma.

Authors:  Pradeep Kumar; Amit Kumar Singh; Pooja Verma; Kavindra Nath Tiwari; Sunil Kumar Mishra
Journal:  Med Oncol       Date:  2022-07-19       Impact factor: 3.738

2.  Cesdiurins I-III, steroidal saponins from Cestrum diurnum L.

Authors:  Mostafa A Fouad; Khaled M Mohamed; Mohamed S Kamel; Katsuyoshi Matsunami; Hideaki Otsuka
Journal:  J Nat Med       Date:  2007-12-01       Impact factor: 2.343

3.  Strange little flies in the big city: exotic flower-breeding drosophilidae (Diptera) in urban Los Angeles.

Authors:  David Grimaldi; Paul S Ginsberg; Lesley Thayer; Shane McEvey; Martin Hauser; Michael Turelli; Brian Brown
Journal:  PLoS One       Date:  2015-04-29       Impact factor: 3.240

4.  A Total of Eight Novel Steroidal Glycosides Based on Spirostan, Furostan, Pseudofurostan, and Cholestane from the Leaves of Cestrum newellii.

Authors:  Tomoki Iguchi; Naoki Takahashi; Yoshihiro Mimaki
Journal:  Molecules       Date:  2020-09-28       Impact factor: 4.411

  4 in total

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