Literature DB >> 11170622

Medicinal chemistry of neuronal voltage-gated sodium channel blockers.

T Anger1, D J Madge, M Mulla, D Riddall.   

Abstract

Entities:  

Mesh：

Substances：

Year:  2001        PMID： 11170622     DOI： 10.1021/jm000155h

Source DB:  PubMed          Journal:  J Med Chem        ISSN： 0022-2623            Impact factor:   7.446


× No keyword cloud information.
  19 in total

1.  Discovery of diphenyl amine based sodium channel blockers, effective against hNav1.2.

Authors:  Debjani P Hudgens; Catherine Taylor; Timothy W Batts; Manoj K Patel; Milton L Brown
Journal:  Bioorg Med Chem       Date:  2006-10-10       Impact factor: 3.641

2.  Aconitum and Delphinium sp. alkaloids as antagonist modulators of voltage-gated Na+ channels. AM1/DFT electronic structure investigations and QSAR studies.

Authors:  Malakhat A Turabekova; Bakhtiyor F Rasulev; Mikhail G Levkovich; Nasrulla D Abdullaev; Jerzy Leszczynski
Journal:  Comput Biol Chem       Date:  2007-10-24       Impact factor: 2.877

3.  Enaminones 8: CoMFA and CoMSIA studies on some anticonvulsant enaminones.

Authors:  Patrice L Jackson; K R Scott; William M Southerland; Ya-Yin Fang
Journal:  Bioorg Med Chem       Date:  2008-11-13       Impact factor: 3.641

4.  Synthesis and evaluation of hermitamides A and B as human voltage-gated sodium channel blockers.

Authors:  Eliseu O De Oliveira; Kristin M Graf; Manoj K Patel; Aparna Baheti; Hye-Sik Kong; Linda H MacArthur; Sivanesan Dakshanamurthy; Kan Wang; Milton L Brown; Mikell Paige
Journal:  Bioorg Med Chem       Date:  2011-05-30       Impact factor: 3.641

Review 5.  Ion channels as drug targets in central nervous system disorders.

Authors:  A M Waszkielewicz; A Gunia; N Szkaradek; K Słoczyńska; S Krupińska; H Marona
Journal:  Curr Med Chem       Date:  2013       Impact factor: 4.530

6.  Mechanism of action of sodium channel blocker insecticides (SCBIs) on insect sodium channels.

Authors:  Kristopher S Silver; Weizhong Song; Yoshiko Nomura; Vincent L Salgado; Ke Dong
Journal:  Pestic Biochem Physiol       Date:  2010-06-01       Impact factor: 3.963

7.  A mutant of the Buthus martensii Karsch antitumor-analgesic peptide exhibits reduced inhibition to hNav1.4 and hNav1.5 channels while retaining analgesic activity.

Authors:  Yijia Xu; Xiangxue Meng; Xue Hou; Jianfang Sun; Xiaohua Kong; Yuqi Sun; Zeyu Liu; Yuanyuan Ma; Ye Niu; Yongbo Song; Yong Cui; Mingyi Zhao; Jinghai Zhang
Journal:  J Biol Chem       Date:  2017-09-18       Impact factor: 5.157

8.  Functional Modulation of Voltage-Gated Sodium Channels by a FGF14-Based Peptidomimetic.

Authors:  Syed R Ali; Zhiqing Liu; Miroslav N Nenov; Oluwarotimi Folorunso; Aditya Singh; Federico Scala; Haiying Chen; T F James; Musaad Alshammari; Neli I Panova-Elektronova; Mark Andrew White; Jia Zhou; Fernanda Laezza
Journal:  ACS Chem Neurosci       Date:  2018-02-06       Impact factor: 4.418

9.  Gallium(III)-catalyzed cycloisomerization approach to the diterpenoid alkaloids: construction of the core structure for the hetidines and hetisines.

Authors:  Amy M Hamlin; Felipe de Jesus Cortez; David Lapointe; Richmond Sarpong
Journal:  Angew Chem Int Ed Engl       Date:  2013-03-26       Impact factor: 15.336

10.  De novo synthesis of modified saxitoxins for sodium ion channel study.

Authors:  Brian M Andresen; J Du Bois
Journal:  J Am Chem Soc       Date:  2009-09-09       Impact factor: 15.419
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.