Literature DB >> 1117053

Aromatization of androstenedione by isolated human hairs.

H U Schweikert, L Milewich, J D Wilson.   

Abstract

The formation of (3-H) estrone has been demonstrated in human anagen scalp hair roots incubated with (1, 2, 6, 7-3H) androstenedione, and approximate rates of formation of 0.2 pmol of estrone/mg DNA/h were observed. Thus, hair is a potential site for the extraglandular formation of estrogen in man.

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Year:  1975        PMID： 1117053     DOI： 10.1210/jcem-40-3-413

Source DB:  PubMed          Journal:  J Clin Endocrinol Metab        ISSN： 0021-972X            Impact factor:   5.958


  16 in total

Review 1.  Clinical pharmacokinetics of endocrine agents used in advanced breast cancer.

Authors:  P E Lønning; E A Lien; S Lundgren; S Kvinnsland
Journal:  Clin Pharmacokinet       Date:  1992-05       Impact factor: 6.447

2.  An estrogen receptor pathway regulates the telogen-anagen hair follicle transition and influences epidermal cell proliferation.

Authors:  H S Oh; R C Smart
Journal:  Proc Natl Acad Sci U S A       Date:  1996-10-29       Impact factor: 11.205

Review 3.  Anabolic-androgenic steroids: In cell culture.

Authors:  C D Kochakian; A A Welder
Journal:  In Vitro Cell Dev Biol Anim       Date:  1993-06       Impact factor: 2.416

4.  In vivo influence of androgens on the cell kinetics and chromatin pattern of the MXT mouse mammary tumor treated or not by aminoglutethimide.

Authors:  Y de Launoit; R Kiss
Journal:  J Cancer Res Clin Oncol       Date:  1989       Impact factor: 4.553

5.  [Hormonal principles in normal and pathologic somatic sexual development].

Authors:  H U Schweikert; F Neumann
Journal:  Klin Wochenschr       Date:  1986-01-15

Review 6.  Estrogens in Male Physiology.

Authors:  Paul S Cooke; Manjunatha K Nanjappa; CheMyong Ko; Gail S Prins; Rex A Hess
Journal:  Physiol Rev       Date:  2017-07-01       Impact factor: 37.312

Review 7.  Aromatase inhibitors and inactivators for breast cancer therapy.

Authors:  Per E Lønning
Journal:  Drugs Aging       Date:  2002       Impact factor: 3.923

Review 8.  Mechanisms of action of aminoglutethimide as endocrine therapy of breast cancer.

Authors:  P E Lønning; S Kvinnsland
Journal:  Drugs       Date:  1988-06       Impact factor: 9.546

Review 9.  Suppression of estrogens with aminoglutethimide and hydrocortisone (medical adrenalectomy) as treatment of advanced breast carcinoma: a review.

Authors:  R J Santen
Journal:  Breast Cancer Res Treat       Date:  1981       Impact factor: 4.872

10.  pathogenesis of the henny feathering trait in the Sebright bantam chicken. Increased conversion of androgen to estrogen in skin.

Authors:  F W George; J D Wilson
Journal:  J Clin Invest       Date:  1980-07       Impact factor: 14.808
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