Literature DB >> 11169548

Screening for fetal alcohol syndrome in primary schools: a feasibility study.

S K Clarren1, S P Randels, M Sanderson, R M Fineman.   

Abstract

BACKGROUND: This project was undertaken as a feasibility study to determine the possibility of screening for fetal alcohol syndrome (FAS) in early school-age children for epidemiological and interventional purposes.
METHODS: All elementary schools in two counties in Washington State were asked to screen first graders for possible FAS. A child was screen positive if found to be growth deficient, to have certain specific facial abnormalities, or have a known history of substantial alcohol exposure in gestation. All screen-positive children were invited to "special diagnostic clinics" for final diagnosis and treatment planning.
RESULTS: In County A, virtually all students were screened. In County B only about 25% of children were screened. This difference was related to the number of schools that agreed to participate in the project and the methods employed by each county to obtain parental permission. In each county, only about one-half of the screen-positive children were seen in the special clinics for diagnostic considerations. Only one of the seven children found to have FAS had been diagnosed previously. The minimal prevalence of FAS in County A was 3.1 in 1,000 students. The minimal prevalence of FAS in County B could not be calculated. The most efficient component in the screening process leading to a diagnosis of FAS was finding the specific facial features of the disorder. The diagnosis of FAS was generally helpful in improving educational planning.
CONCLUSIONS: This study demonstrated that population-based FAS screening within a school system may be possible, but participation is dependent on local trust and understanding of the project before its inception within the schools and the community at large.

Entities:  

Mesh:

Year:  2001        PMID: 11169548     DOI: 10.1002/1096-9926(200101)63:1<3::AID-TERA1001>3.0.CO;2-P

Source DB:  PubMed          Journal:  Teratology        ISSN: 0040-3709


  22 in total

1.  Calcium-mediated repression of β-catenin and its transcriptional signaling mediates neural crest cell death in an avian model of fetal alcohol syndrome.

Authors:  George R Flentke; Ana Garic; Ed Amberger; Marcos Hernandez; Susan M Smith
Journal:  Birth Defects Res A Clin Mol Teratol       Date:  2011-05-31

2.  The epidemiology of fetal alcohol syndrome and partial FAS in a South African community.

Authors:  Philip A May; J Phillip Gossage; Anna-Susan Marais; Colleen M Adnams; H Eugene Hoyme; Kenneth L Jones; Luther K Robinson; Nathaniel C O Khaole; Cudore Snell; Wendy O Kalberg; Loretta Hendricks; Lesley Brooke; Chandra Stellavato; Denis L Viljoen
Journal:  Drug Alcohol Depend       Date:  2006-11-28       Impact factor: 4.492

3.  CaMKII activation is a novel effector of alcohol's neurotoxicity in neural crest stem/progenitor cells.

Authors:  Ana Garic; George R Flentke; Ed Amberger; Marcos Hernandez; Susan M Smith
Journal:  J Neurochem       Date:  2011-05-13       Impact factor: 5.372

4.  Alcohol use and abuse in pregnancy: an evaluation of the merits of screening.

Authors:  Matt Hicks; Reginald S Sauve; Andrew W Lyon; Margaret Clarke; Suzanne Tough
Journal:  Can Child Adolesc Psychiatr Rev       Date:  2003-08

5.  Prevention of secondary conditions in fetal alcohol spectrum disorders: identification of systems-level barriers.

Authors:  Christie L M Petrenko; Naira Tahir; Erin C Mahoney; Nancy P Chin
Journal:  Matern Child Health J       Date:  2014-08

6.  Population differences in dysmorphic features among children with fetal alcohol spectrum disorders.

Authors:  Philip A May; J Phillip Gossage; Matthew Smith; Barbara G Tabachnick; Luther K Robinson; Melanie Manning; Mauro Cecanti; Kenneth Lyons Jones; Nathaniel Khaole; David Buckley; Wendy O Kalberg; Phyllis M Trujillo; H Eugene Hoyme
Journal:  J Dev Behav Pediatr       Date:  2010-05       Impact factor: 2.225

Review 7.  Global Prevalence of Fetal Alcohol Spectrum Disorder Among Children and Youth: A Systematic Review and Meta-analysis.

Authors:  Shannon Lange; Charlotte Probst; Gerrit Gmel; Jürgen Rehm; Larry Burd; Svetlana Popova
Journal:  JAMA Pediatr       Date:  2017-10-01       Impact factor: 16.193

8.  Approaching the prevalence of the full spectrum of fetal alcohol spectrum disorders in a South African population-based study.

Authors:  Philip A May; Jason Blankenship; Anna-Susan Marais; J Phillip Gossage; Wendy O Kalberg; Ronel Barnard; Marlene De Vries; Luther K Robinson; Colleen M Adnams; David Buckley; Melanie Manning; Kenneth L Jones; Charles Parry; H Eugene Hoyme; Soraya Seedat
Journal:  Alcohol Clin Exp Res       Date:  2012-12-14       Impact factor: 3.455

9.  Prevalence and characteristics of fetal alcohol syndrome and partial fetal alcohol syndrome in a Rocky Mountain Region City.

Authors:  Philip A May; Carol Keaster; Rosemary Bozeman; Joelene Goodover; Jason Blankenship; Wendy O Kalberg; David Buckley; Marita Brooks; Julie Hasken; J Phillip Gossage; Luther K Robinson; Melanie Manning; H Eugene Hoyme
Journal:  Drug Alcohol Depend       Date:  2015-08-14       Impact factor: 4.492

10.  Prenatal choline supplementation mitigates the adverse effects of prenatal alcohol exposure on development in rats.

Authors:  Jennifer D Thomas; Elizabeth J Abou; Hector D Dominguez
Journal:  Neurotoxicol Teratol       Date:  2009-07-16       Impact factor: 3.763

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.