Literature DB >> 11167341

Estimation or quantification of tumour volume? CT study on irregular phantoms.

M Tiitola1, L Kivisaari, P Tervahartiala, M Palomäki, R P Kivisaari, P Mankinen, T Vehmas.   

Abstract

PURPOSE: To compare radiologists' subjective size estimation to computerised volume quantification of tumour-like phantoms in spiral CT.
MATERIAL AND METHODS: Eight tubular phantoms with the inside irregularly covered with silicone (8.7-31.6 ml) were imaged. The phantoms were pairwise compared to analyse the differences in silicone volumes. The observers, 2 radiologists and 2 residents, used both subjective image analysis (2 sessions) and computerised volume quantification (1 session). Accuracy and observer agreement of both methods were calculated.
RESULTS: Subjective size estimation was correct in 51% (mean weighted kappa, Kqw=0.73). Using four observers' mean value (Kqw=0.81) or median value (Kqw=0.77) slightly improved the results. Average intra-observer agreement was better than average interobserver agreement. In computerised volume quantification 70% of all classifications were correct (mean Kqw=0.85). The results were moderate even when every second or fourth slice were measured.
CONCLUSION: Subjective size estimation of irregular tumours should be repeatedly performed by the same observer, or by using the mean or median estimate of several observers. Computer-based methods are even more reliable and their use is especially recommended for film readers with limited radiological experience. Only every fourth slice may be measured without a major loss of measurement accuracy.

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Year:  2001        PMID: 11167341     DOI: 10.1080/028418501127346332

Source DB:  PubMed          Journal:  Acta Radiol        ISSN: 0284-1851            Impact factor:   1.701


  1 in total

1.  Prognostic value of gross tumor volume delineated by FDG-PET-CT based radiotherapy treatment planning in patients with locally advanced pancreatic cancer treated with chemoradiotherapy.

Authors:  Cem Parlak; Erkan Topkan; Cem Onal; Mehmet Reyhan; Ugur Selek
Journal:  Radiat Oncol       Date:  2012-03-19       Impact factor: 3.481

  1 in total

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