Literature DB >> 11166718

Serotonin 2A receptor-like immunoreactivity is detected in astrocytes but not in oligodendrocytes of rat spinal cord.

M Maxishima1, T Shiga, F Shutoh, S Hamada, T Maeshima, N Okado.   

Abstract

The distribution of the serotonin 2A (5-HT2A) receptor in glial cells in the white matter of rat spinal cord was immunohistochemically examined with specific antibodies against the 5-HT2A receptor. 5-HT2A receptor-like immunoreactivity was detected in astrocytes that were identified by an antibody against the glial fibrillary acidic protein. In contrast, 5-HT2A receptor-like immunoreactivity was not observed in oligodendrocytes.

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Year:  2001        PMID： 11166718     DOI： 10.1016/s0006-8993(00)03150-4

Source DB:  PubMed          Journal:  Brain Res        ISSN： 0006-8993            Impact factor:   3.252


  11 in total

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4.  Exposure to serotonin adversely affects oligodendrocyte development and myelination in vitro.

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7.  Serotonin receptor 2A blocker (risperidone) has no effect on human polyomavirus JC infection of primary human fetal glial cells.

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Review 8.  Serotonergic Modulation of Nociceptive Circuits in Spinal Cord Dorsal Horn.

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10.  Motor Cortex Stimulation Reversed Hypernociception, Increased Serotonin in Raphe Neurons, and Caused Inhibition of Spinal Astrocytes in a Parkinson's Disease Rat Model.

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