Literature DB >> 11166339

Orexin A excites serotonergic neurons in the dorsal raphe nucleus of the rat.

R E Brown1, O Sergeeva, K S Eriksson, H L Haas.   

Abstract

Orexin A (10-300 nM) strongly excited dorsal raphe serotonergic neurons maintained in vitro. The depolarization persisted in the presence of tetrodotoxin (TTX, 0.5 microM) and was associated with an increase in input resistance. These results have relevance in the context of food intake regulation and the disease, narcolepsy.

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Year:  2001        PMID: 11166339     DOI: 10.1016/s0028-3908(00)00178-7

Source DB:  PubMed          Journal:  Neuropharmacology        ISSN: 0028-3908            Impact factor:   5.250


  76 in total

1.  Release of hypocretin (orexin) during waking and sleep states.

Authors:  Lyudmila I Kiyashchenko; Boris Y Mileykovskiy; Nigel Maidment; Hoa A Lam; Ming-Fung Wu; Joshi John; John Peever; Jerome M Siegel
Journal:  J Neurosci       Date:  2002-07-01       Impact factor: 6.167

2.  Selective enhancement of synaptic inhibition by hypocretin (orexin) in rat vagal motor neurons: implications for autonomic regulation.

Authors:  Scott F Davis; Kevin W Williams; Weiye Xu; Nicholas R Glatzer; Bret N Smith
Journal:  J Neurosci       Date:  2003-05-01       Impact factor: 6.167

3.  [The neurotransmitter, hypocretin. An overview].

Authors:  C Baumann; C Bassetti
Journal:  Nervenarzt       Date:  2004-04       Impact factor: 1.214

Review 4.  Hypocretin/orexin involvement in reward and reinforcement.

Authors:  Rodrigo A España
Journal:  Vitam Horm       Date:  2012       Impact factor: 3.421

5.  Influence of inhibitory serotonergic inputs to orexin/hypocretin neurons on the diurnal rhythm of sleep and wakefulness.

Authors:  Sawako Tabuchi; Tomomi Tsunematsu; Thomas S Kilduff; Shouta Sugio; Ming Xu; Kenji F Tanaka; Satoru Takahashi; Makoto Tominaga; Akihiro Yamanaka
Journal:  Sleep       Date:  2013-09-01       Impact factor: 5.849

6.  Functional link between the hypocretin and serotonin systems in the neural control of breathing and central chemosensitivity.

Authors:  Andrea E Corcoran; George B Richerson; Michael B Harris
Journal:  J Neurophysiol       Date:  2015-04-15       Impact factor: 2.714

7.  The wake-promoting peptide orexin-B inhibits glutamatergic transmission to dorsal raphe nucleus serotonin neurons through retrograde endocannabinoid signaling.

Authors:  Samir Haj-Dahmane; Roh-Yu Shen
Journal:  J Neurosci       Date:  2005-01-26       Impact factor: 6.167

8.  Behavioral correlates of activity in identified hypocretin/orexin neurons.

Authors:  Boris Y Mileykovskiy; Lyudmila I Kiyashchenko; Jerome M Siegel
Journal:  Neuron       Date:  2005-06-02       Impact factor: 17.173

Review 9.  Genetic association, seasonal infections and autoimmune basis of narcolepsy.

Authors:  Abinav Kumar Singh; Josh Mahlios; Emmanuel Mignot
Journal:  J Autoimmun       Date:  2013-03-13       Impact factor: 7.094

10.  Dual orexin actions on dorsal raphe and laterodorsal tegmentum neurons: noisy cation current activation and selective enhancement of Ca2+ transients mediated by L-type calcium channels.

Authors:  K A Kohlmeier; S Watanabe; C J Tyler; S Burlet; C S Leonard
Journal:  J Neurophysiol       Date:  2008-07-30       Impact factor: 2.714

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