Literature DB >> 11165926

Clostridium difficile toxin and faecal lactoferrin assays in adult patients.

C Vaishnavi1, D Bhasin, R Kochhar, K Singh.   

Abstract

Clostridium difficile is the primary aetiological agent of antibiotic-associated diarrhoea. The faecal lactoferrin (FL) assay is a simple in vitro test which is highly sensitive to the presence of a marker of polymorphonuclear cells. We evaluated the use of the FL assay in conjunction with the C. difficile toxin assay in faecal samples obtained from 231 adult patients. The relationship between C. difficile toxin and FL in both negative and positive status was highly significant statistically (P < 0.001). Therefore, the FL assay performed simultaneously with the C. difficile toxin assay can help rule out asymptomatic carriage of C. difficile.

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Year:  2000        PMID： 11165926     DOI： 10.1016/s1286-4579(00)01343-5

Source DB:  PubMed          Journal:  Microbes Infect        ISSN： 1286-4579            Impact factor:   2.700


  9 in total

1.  Hospital-acquired Clostridium difficile infection: determinants for severe disease.

Authors:  J M Wenisch; D Schmid; H-W Kuo; E Simons; F Allerberger; V Michl; P Tesik; G Tucek; C Wenisch
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2011-12-31       Impact factor: 3.267

2.  Diagnostic approach to Clostridium difficile infection.

Authors:  Chetana Vaishnavi
Journal:  Indian J Gastroenterol       Date:  2010-08-18

Review 3.  Clostridium difficile infection: clinical spectrum and approach to management.

Authors:  Chetana Vaishnavi
Journal:  Indian J Gastroenterol       Date:  2011-12-20

4.  Prevalence and clinical course of Clostridium difficile infection in a tertiary-care hospital: a retrospective analysis.

Authors:  Meghraj Ingle; Abhijit Deshmukh; Devendra Desai; Philip Abraham; Anand Joshi; Camilla Rodrigues; Ranjit Mankeshwar
Journal:  Indian J Gastroenterol       Date:  2011-05-07

Review 5.  Host response to Clostridium difficile infection: Diagnostics and detection.

Authors:  Elena A Usacheva; Jian-P Jin; Lance R Peterson
Journal:  J Glob Antimicrob Resist       Date:  2016-09-20       Impact factor: 4.035

6.  Clostridium difficile as a cause of acute diarrhea: a prospective study in a tertiary care center.

Authors:  Meghraj Ingle; Abhijit Deshmukh; Devendra Desai; Philip Abraham; Anand Joshi; Tarun Gupta; Camilla Rodrigues
Journal:  Indian J Gastroenterol       Date:  2013-03-24

7.  MAPK-activated protein kinase 2 contributes to Clostridium difficile-associated inflammation.

Authors:  Linda D Bobo; Rana E El Feghaly; Yee-Shiuan Chen; Erik R Dubberke; Zhuolin Han; Alexandra H Baker; Jinmei Li; Carey-Ann D Burnham; David B Haslam
Journal:  Infect Immun       Date:  2012-12-21       Impact factor: 3.441

8.  Toxigenic Clostridium difficile isolates from clinically significant diarrhoea in patients from a tertiary care centre.

Authors:  Meenakshi Singh; Chetana Vaishnavi; Rakesh Kochhar; Safrun Mahmood
Journal:  Indian J Med Res       Date:  2017-06       Impact factor: 2.375

9.  Calprotectin and lactoferrin faecal levels in patients with Clostridium difficile infection (CDI): a prospective cohort study.

Authors:  Andrew Swale; Fabio Miyajima; Paul Roberts; Amanda Hall; Margaret Little; Mike B J Beadsworth; Nick J Beeching; Ruwanthi Kolamunnage-Dona; Chris M Parry; Munir Pirmohamed
Journal:  PLoS One       Date:  2014-08-29       Impact factor: 3.240
  9 in total

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