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Literature DB >> 11165790

Differentiation of electrical excitability in motoneurons.

N C Spitzer¹, A Vincent, N J Lautermilch.

Abstract

Investigation of the differentiation of electrical properties of motoneurons has been stimulated by the importance of these neurons for embryonic behavior and facilitated by their experimental accessibility. In this review, we examine the development of different patterns of excitability and their functions, and discuss the emergence of repetitive firing and localization of ion channels in axons and dendrites. Finally, we summarize studies of the role of extrinsic factors in differentiation. These changes associated with differentiation of young motoneurons may presage those occurring later in the context of plasticity in the mature nervous system.

Entities: Disease

Mesh：

Substances：
Ion Channels

Year: 2000 PMID： 11165790 DOI： 10.1016/s0361-9230(00)00388-9

Source DB: PubMed Journal: Brain Res Bull ISSN： 0361-9230 Impact factor: 4.077

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Cited

9 in total

Review 1. Phylogenetic, ontogenetic and adult adaptive plasticity of rhythmic neural networks: a common neuromodulatory mechanism?

Authors: V S Fénelon; Y Le Feuvre; P Meyrand
Journal: J Comp Physiol A Neuroethol Sens Neural Behav Physiol Date: 2004-06-25 Impact factor: 1.836

2. Functional and molecular clues reveal precursor-like cells and immature neurones in the turtle spinal cord.

Authors: Raúl E Russo; Anabel Fernández; Cecilia Reali; Milka Radmilovich; Omar Trujillo-Cenóz
Journal: J Physiol Date: 2004-08-26 Impact factor: 5.182

3. The involvement of Cav3.2/alpha1H T-type calcium channels in excitability of mouse embryonic primary vestibular neurones.

Authors: Laurence Autret; Ilana Mechaly; Frédérique Scamps; Jean Valmier; Philippe Lory; Gilles Desmadryl
Journal: J Physiol Date: 2005-06-16 Impact factor: 5.182

9. Transgenic GDNF Positively Influences Proliferation, Differentiation, Maturation and Survival of Motor Neurons Produced from Mouse Embryonic Stem Cells.

Authors: Daniel Cortés; Yolanda Robledo-Arratia; Ricardo Hernández-Martínez; Itzel Escobedo-Ávila; José Bargas; Iván Velasco
Journal: Front Cell Neurosci Date: 2016-09-12 Impact factor: 5.505

9 in total

Differentiation of electrical excitability in motoneurons.

Review 1. Phylogenetic, ontogenetic and adult adaptive plasticity of rhythmic neural networks: a common neuromodulatory mechanism?

2. Functional and molecular clues reveal precursor-like cells and immature neurones in the turtle spinal cord.

3. The involvement of Cav3.2/alpha1H T-type calcium channels in excitability of mouse embryonic primary vestibular neurones.

4. GABAergic signalling in a neurogenic niche of the turtle spinal cord.

5. Enigmatic central canal contacting cells: immature neurons in "standby mode"?

6. Characterization of voltage-gated potassium channels in human neural progenitor cells.

7. Activity-dependent alternative splicing increases persistent sodium current and promotes seizure.

Review 8. Blurring the boundaries: developmental and activity-dependent determinants of neural circuits.

9. Transgenic GDNF Positively Influences Proliferation, Differentiation, Maturation and Survival of Motor Neurons Produced from Mouse Embryonic Stem Cells.