| Literature DB >> 11165764 |
L Bianchi1, D M Miller, A L George.
Abstract
In this study, we report the complete cDNA sequence, genomic organization and expression pattern of the Caenorhabditis elegans ClC chloride channel gene, clh-6. Two different types of reporter gene fusions suggest that clh-6 expression is restricted to two gamma-aminobutyric acid-ergic RME neurons. These results are in striking contrast with the wide tissue distribution of messenger RNA for the related mammalian isoforms, CIC-6 and CIC-7. The restricted expression pattern of clh-6 provides a unique opportunity to study the biological function of a neuronal CIC chloride channel.Entities:
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Year: 2001 PMID： 11165764 DOI： 10.1016/s0304-3940(01)01525-7
Source DB: PubMed Journal: Neurosci Lett ISSN： 0304-3940 Impact factor: 3.046