K Kumar1, M Kelly. 1. Department of Surgery, Section of Neurosurgery, The Regina General Hospital, University of Saskatchewan, Regina, Saskatchewan, Canada.
Abstract
BACKGROUND: Pituitary adenomas are considered benign tumors and metastases are seen when the tumor shows malignant transformation. CASE DESCRIPTION: We present a case of a benign pituitary adenoma with multiple dural metastasis without malignant transformation throughout its course. At all times, the pituitary adenoma remained benign as seen by a lack of nuclear pleomorphism, nuclear atypia, vascular invasion, and absence of immunohistochemical staining for p53 protein. CONCLUSION: This is a rare example of dural metastasis from a benign pituitary adenoma. The authors believe this is the fourth reported case of this type in the literature.
BACKGROUND: Pituitary adenomas are considered benign tumors and metastases are seen when the tumor shows malignant transformation. CASE DESCRIPTION: We present a case of a benign pituitary adenoma with multiple dural metastasis without malignant transformation throughout its course. At all times, the pituitary adenoma remained benign as seen by a lack of nuclear pleomorphism, nuclear atypia, vascular invasion, and absence of immunohistochemical staining for p53 protein. CONCLUSION: This is a rare example of dural metastasis from a benign pituitary adenoma. The authors believe this is the fourth reported case of this type in the literature.
Authors: Ashley L B Raghu; Megan C Everson; Ahmed Helal; Satoshi Kiyofuji; Michelle J Clarke; Michael J Link Journal: J Neurol Surg B Skull Base Date: 2021-03-01