| Literature DB >> 11163993 |
K Kogure1, T Itoh, O Okuda, K Hayashi, M Ueno.
Abstract
We examined the effects of pretreatment of monkey kidney normal cells (CV-1) and human cervical tumor cells (HeLa) with membrane fusible erythrocyte ghosts (MFEG) encapsulating superoxide dismutase (SOD-MFEG) on adriamycin (ADM) cytotoxicity. The decrease in CV-1 cells with ADM was inhibited markedly, and the initiation of decrease in HeLa cells was delayed for 2 days by the pretreatment with SOD-MFEG, indicating that the delivered SOD held the activity in the cells.Entities:
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Year: 2000 PMID: 11163993 DOI: 10.1016/s0378-5173(00)00579-2
Source DB: PubMed Journal: Int J Pharm ISSN: 0378-5173 Impact factor: 5.875