Literature DB >> 11163993

The delivery of protein into living cells by use of membrane fusible erythrocyte ghosts.

K Kogure1, T Itoh, O Okuda, K Hayashi, M Ueno.   

Abstract

We examined the effects of pretreatment of monkey kidney normal cells (CV-1) and human cervical tumor cells (HeLa) with membrane fusible erythrocyte ghosts (MFEG) encapsulating superoxide dismutase (SOD-MFEG) on adriamycin (ADM) cytotoxicity. The decrease in CV-1 cells with ADM was inhibited markedly, and the initiation of decrease in HeLa cells was delayed for 2 days by the pretreatment with SOD-MFEG, indicating that the delivered SOD held the activity in the cells.

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Year:  2000        PMID: 11163993     DOI: 10.1016/s0378-5173(00)00579-2

Source DB:  PubMed          Journal:  Int J Pharm        ISSN: 0378-5173            Impact factor:   5.875


  1 in total

Review 1.  Application and Utility of Liposomal Neuroprotective Agents and Biomimetic Nanoparticles for the Treatment of Ischemic Stroke.

Authors:  Tatsuya Fukuta; Naoto Oku; Kentaro Kogure
Journal:  Pharmaceutics       Date:  2022-02-04       Impact factor: 6.321

  1 in total

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