Literature DB >> 11163860

Proinflammatory and antitumor properties of interleukin-18 in the gastrointestinal tract.

F Pages1, A Berger, S Lebel-Binay, F Zinzindohoue, C Danel, B Piqueras, O Carriere, N Thiounn, P H Cugnenc, W H Fridman.   

Abstract

Interleukin-18 (IL-18) plays a central role in the immune response by acting on Th1 cell differentiation, cell-mediated cytotoxicity and inflammation. The role of IL-18 in cancers and inflammatory diseases is discussed in the light of our investigations on IL-18 synthesis in normal colonic mucosa, colonic cancer and Crohn's disease (CD).

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Year:  2000        PMID： 11163860     DOI： 10.1016/s0165-2478(00)00285-6

Source DB:  PubMed          Journal:  Immunol Lett        ISSN： 0165-2478            Impact factor:   3.685


  8 in total

1.  Genetic variants of the interleukin-18 promoter region (-607) influence the course of necrotising enterocolitis in very low birth weight neonates.

Authors:  Erika Héninger; András Treszl; István Kocsis; Beáta Dérfalvi; Tivadar Tulassay; Barna Vásárhelyi
Journal:  Eur J Pediatr       Date:  2002-07       Impact factor: 3.183

2.  Genetic polymorphism of interleukin-18 gene promoter region in rheumatoid arthritis patients from southern India.

Authors:  Varun Chaithanya Gurram; Sunil Kumar Polipalli; Vijay Kumar Karra; Madhavi Puppala; Sanjeev Kumar Pandey; Seema Kapoor; Ashok Kumar; Sudhakar Godi
Journal:  J Clin Diagn Res       Date:  2014-06-20

3.  Association of genetic polymorphisms of interleukins with gastric cancer and precancerous gastric lesions in a high-risk Chinese population.

Authors:  Yu-Mei Wang; Zhe-Xuan Li; Fu-Bing Tang; Yang Zhang; Tong Zhou; Lian Zhang; Jun-Ling Ma; Wei-Cheng You; Kai-Feng Pan
Journal:  Tumour Biol       Date:  2015-09-10

4.  Interleukin 18 and associated markers of T helper cell type 1 activity in coeliac disease.

Authors:  V M Salvati; T T MacDonald; M Bajaj-Elliott; M Borrelli; A Staiano; S Auricchio; R Troncone; G Monteleone
Journal:  Gut       Date:  2002-02       Impact factor: 23.059

5.  The relationship between soluble receptor of interleukin-6 with angiogenic cytokines and proliferation markers in multiple myeloma.

Authors:  George Tsirakis; Constantina A Pappa; Maria Kaparou; Anna Boula; Vaitsa Katsomitrou; Athina Xekalou; Stavroula Kyriakaki; Michael G Alexandrakis
Journal:  Tumour Biol       Date:  2012-12-16

6.  The immunogenicity of colorectal cancers with high-degree microsatellite instability.

Authors:  Ayan Banerjea; Stephen A Bustin; Sina Dorudi
Journal:  World J Surg Oncol       Date:  2005-05-12       Impact factor: 2.754

Review 7.  Cytokine-Induced Modulation of Colorectal Cancer.

Authors:  Lukas F Mager; Marie-Hélène Wasmer; Tilman T Rau; Philippe Krebs
Journal:  Front Oncol       Date:  2016-04-19       Impact factor: 6.244

8.  The Role of Chromosomal Instability and Epigenetics in Colorectal Cancers Lacking β-Catenin/TCF Regulated Transcription.

Authors:  Wael M Abdel-Rahman; Johanna E Lotsari-Salomaa; Sippy Kaur; Anni Niskakoski; Sakari Knuutila; Heikki Järvinen; Jukka-Pekka Mecklin; Päivi Peltomäki
Journal:  Gastroenterol Res Pract       Date:  2016-03-07       Impact factor: 2.260
  8 in total

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