| Literature DB >> 11163392 |
Z Dembic1.
Abstract
The immune system neither discriminates between "Self" and "Nonself", nor it acts when confronting "Danger", rather, it reacts to disruption of tissue integrity allowing its renewal. The "integrity" hypothesis proposes three groups of signals that coordinate actions of dendritic cells and immunocytes during the initiation of the specific immune response, and suggests explanations for tolerance, memory formation, and repertoire selection, including differences with other theories.Mesh:
Year: 2000 PMID: 11163392 DOI: 10.1016/s0161-5890(00)00084-5
Source DB: PubMed Journal: Mol Immunol ISSN: 0161-5890 Impact factor: 4.407