Literature DB >> 11163156

Mitotic checkpoints: from yeast to cancer.

K Wassmann1, R Benezra.   

Abstract

Separation of chromosomes during mitosis is monitored by a checkpoint that leads to cell-cycle arrest if the chromosomes are not properly attached to the mitotic spindle. Molecular mechanisms controlling this checkpoint have been identified. In addition, loss of this checkpoint has been shown to result in chromosome missegregation in higher eukaryotes and may contribute to the genomic instability observed in human cancers.

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Year:  2001        PMID： 11163156     DOI： 10.1016/s0959-437x(00)00161-1

Source DB:  PubMed          Journal:  Curr Opin Genet Dev        ISSN： 0959-437X            Impact factor:   5.578


  65 in total

1.  Bub3 interaction with Mad2, Mad3 and Cdc20 is mediated by WD40 repeats and does not require intact kinetochores.

Authors:  R Fraschini; A Beretta; L Sironi; A Musacchio; G Lucchini; S Piatti
Journal:  EMBO J       Date:  2001-12-03       Impact factor: 11.598

2.  The kinetochore protein Bub1 participates in the DNA damage response.

Authors:  Chunying Yang; Haibo Wang; Yiran Xu; Kathryn L Brinkman; Hiromichi Ishiyama; Stephen T C Wong; Bo Xu
Journal:  DNA Repair (Amst)       Date:  2011-11-09

Review 3.  Cell cycle control mechanisms in B-1 and B-2 lymphoid subsets.

Authors:  Michael J Piatelli; Debra Tanguay; Thomas L Rothstein; Thomas C Chiles
Journal:  Immunol Res       Date:  2003       Impact factor: 2.829

4.  Mad2 phosphorylation regulates its association with Mad1 and the APC/C.

Authors:  Katja Wassmann; Vasco Liberal; Robert Benezra
Journal:  EMBO J       Date:  2003-02-17       Impact factor: 11.598

5.  Conformation-specific binding of p31(comet) antagonizes the function of Mad2 in the spindle checkpoint.

Authors:  Guohong Xia; Xuelian Luo; Toshiyuki Habu; Josep Rizo; Tomohiro Matsumoto; Hongtao Yu
Journal:  EMBO J       Date:  2004-07-15       Impact factor: 11.598

Review 6.  Fine tuning chemotherapy to match BRCA1 status.

Authors:  Melissa Price; Alvaro N A Monteiro
Journal:  Biochem Pharmacol       Date:  2010-05-25       Impact factor: 5.858

7.  MAD1 (mitotic arrest deficiency 1) is a candidate for a tumor suppressor gene in human stomach.

Authors:  Mitsuhiko Osaki; Toshiaki Inoue; Shigeyuki Yamaguchi; Aiko Inaba; Naruo Tokuyasu; Kuan-Teh Jeang; Mitsuo Oshimura; Hisao Ito
Journal:  Virchows Arch       Date:  2007-08-03       Impact factor: 4.064

8.  Spindle checkpoint and apoptotic response in alpha-particle transformed human bronchial epithelial cells.

Authors:  J-L Sui; J An; J-F Sun; Y Chen; D-C Wu; P-K Zhou
Journal:  Radiat Environ Biophys       Date:  2004-12-18       Impact factor: 1.925

9.  Human enhancer of invasion-cluster, a coiled-coil protein required for passage through mitosis.

Authors:  Margret B Einarson; Edna Cukierman; Duane A Compton; Erica A Golemis
Journal:  Mol Cell Biol       Date:  2004-05       Impact factor: 4.272

Review 10.  Can the status of the breast and ovarian cancer susceptibility gene 1 product (BRCA1) predict response to taxane-based cancer therapy?

Authors:  J Thomas De Ligio; Aneliya Velkova; Diego A R Zorio; Alvaro N A Monteiro
Journal:  Anticancer Agents Med Chem       Date:  2009-06       Impact factor: 2.505
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