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Literature DB >> 11163129

Conformational changes during kinesin motility.

Abstract

Nucleotide-dependent movements of the head and neck of kinesin have been visualized by cryoelectron microscopy and have been inferred from single-molecule studies. Key predictions of the hand-over-hand model for dimeric kinesin have been confirmed, and a novel processivity mechanism for the one-headed, kinesin-related motor KIF1A has been discovered.

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Year: 2001 PMID： 11163129 DOI： 10.1016/s0955-0674(00)00169-1

Source DB: PubMed Journal: Curr Opin Cell Biol ISSN： 0955-0674 Impact factor: 8.382

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Cited

35 in total

1. KIF1D is a fast non-processive kinesin that demonstrates novel K-loop-dependent mechanochemistry.

Authors: K R Rogers; S Weiss; I Crevel; P J Brophy; M Geeves; R Cross
Journal: EMBO J Date: 2001-09-17 Impact factor: 11.598

2. Stepping and stretching. How kinesin uses internal strain to walk processively.

Authors: Steven S Rosenfeld; Polly M Fordyce; Geraldine M Jefferson; Peter H King; Steven M Block
Journal: J Biol Chem Date: 2003-03-06 Impact factor: 5.157

3. EPR spectroscopy shows a microtubule-dependent conformational change in the kinesin switch 1 domain.

Authors: Nariman Naber; Sarah Rice; Marija Matuska; Ronald D Vale; Roger Cooke; Edward Pate
Journal: Biophys J Date: 2003-05 Impact factor: 4.033

4. Coordination of kinesin's two heads studied with mutant heterodimers.

Authors: Kuniyoshi Kaseda; Hideo Higuchi; Keiko Hirose
Journal: Proc Natl Acad Sci U S A Date: 2002-11-25 Impact factor: 11.205

5. Fluctuations and randomness of movement of the bead powered by a single kinesin molecule in a force-clamped motility assay: Monte Carlo simulations.

Authors: Yi-der Chen; Bo Yan; Robert J Rubin
Journal: Biophys J Date: 2002-11 Impact factor: 4.033

Conformational changes during kinesin motility.

1. KIF1D is a fast non-processive kinesin that demonstrates novel K-loop-dependent mechanochemistry.

2. Stepping and stretching. How kinesin uses internal strain to walk processively.

3. EPR spectroscopy shows a microtubule-dependent conformational change in the kinesin switch 1 domain.

4. Coordination of kinesin's two heads studied with mutant heterodimers.

5. Fluctuations and randomness of movement of the bead powered by a single kinesin molecule in a force-clamped motility assay: Monte Carlo simulations.

6. What kinesin does at roadblocks: the coordination mechanism for molecular walking.

7. Inhibition of kinesin motility by ADP and phosphate supports a hand-over-hand mechanism.

8. Rapid double 8-nm steps by a kinesin mutant.

9. Kinesin's second step.

10. Measurement of single macromolecule orientation by total internal reflection fluorescence polarization microscopy.