Literature DB >> 11160022

Mechanisms mediating Porphyromonas gingivalis gingipain RgpA-induced oral mucosa inflammation in vivo.

I Rubinstein1, J Potempa, J Travis, X P Gao.   

Abstract

Suffusion of gingipain RgpA (GRgpA) elicited a significant concentration-dependent increase in the clearance of macromolecules from in situ hamster cheek pouch which was attenuated by NPC 17647, a selective bradykinin B(2) receptor antagonist. Leupeptin and a mixture of proteinase inhibitors also attenuated GRgpA-induced responses. These data indicate that GRgpA elicits plasma exudation from in situ oral mucosa in a catalytic site-dependent fashion by elaborating bradykinin.

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Year:  2001        PMID： 11160022      PMCID： PMC98006          DOI： 10.1128/IAI.69.2.1199-1201.2001

Source DB:  PubMed          Journal:  Infect Immun        ISSN： 0019-9567            Impact factor:   3.441


  33 in total

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3.  Cigarette smoke extract attenuates endothelium-dependent arteriolar dilatation in vivo.

Authors:  I Rubenstein; T Yong; S I Rennard; W G Mayhan
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Review 4.  Periodontal disease.

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5.  Implantation of Bacteroides gingivalis in nonhuman primates initiates progression of periodontitis.

Authors:  S C Holt; J Ebersole; J Felton; M Brunsvold; K S Kornman
Journal:  Science       Date:  1988-01-01       Impact factor: 47.728

6.  Quantitation of vasodilator-induced macromolecular leakage by in vivo fluorescent microscopy.

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7.  Role of protein kinase C in bradykinin-induced increases in microvascular permeability.

Authors:  M A Murray; D D Heistad; W G Mayhan
Journal:  Circ Res       Date:  1991-05       Impact factor: 17.367

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Authors:  L R Steranka; S G Farmer; R M Burch
Journal:  FASEB J       Date:  1989-07       Impact factor: 5.191

9.  Activation of hageman factor and prekallikrein and generation of kinin by various microbial proteinases.

Authors:  A Molla; T Yamamoto; T Akaike; S Miyoshi; H Maeda
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10.  Enhancement of acute allergic inflammation by indomethacin is reversed by prostaglandin E2: apparent correlation with in vivo modulation of mediator release.

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  3 in total

1.  E. coli lipopolysaccharide attenuates adenosine A(1) receptor-mediated increase in plasma exudation from the hamster cheek pouch.

Authors:  Xiao-pei Gao; Israel Rubinstein
Journal:  Inflamm Res       Date:  2010-10-06       Impact factor: 4.575

2.  Benzamidine derivatives inhibit the virulence of Porphyromonas gingivalis.

Authors:  E Fröhlich; T Kantyka; K Plaza; K-H Schmidt; W Pfister; J Potempa; S Eick
Journal:  Mol Oral Microbiol       Date:  2012-12-26       Impact factor: 3.563

3.  Bacillus species are present in chewing tobacco sold in the United States and evoke plasma exudation from the oral mucosa.

Authors:  Israel Rubinstein; Gerald W Pedersen
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  3 in total

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